New in JHVS V2I1: Daria Evensen et al. compare six osteogenic media to evaluate their ability to induce aortic valve calcification in vitro using #VICs and #MSCs. The study highlights the complexity of modeling #CAVD and choosing the right conditions.
🔗 shorturl.at/Yqp4Q
#heartvalve #JHVS

Gut microbiota‐derived butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH lactylation and butyrylation Multi-omics sequencing and correlation analysis identified the beneficial role of Faecalibacterium prausnitzii (F. prausnitzii)-derived butyric acid (BA) as a key metabolite in the restoration of val....

Gut #microbiota‐derived #butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH #lactylation and #butyrylation
onlinelibrary.wiley.com/doi/10.1002/...
#CAVD #CVD #microbiome

Excited to have presented our work on #WIN332, a new #HIV #vacccine candidate at the annual #CAVD meeting by the Gates Foundation in Tanzania. Even more excited to have spoken for the first time during a session moderated by one of my postdoctoral students, Maria Belen Palacio. Proud of you! 💫 😍

Thank you to the Gates Foundation for featuring 4 of our studies at the annual #CAVD meeting in Tanzania. Congratulations Marta Tarquis Medina, Austin Kriews, Colby Agostino @colby-agostino.bsky.social and Ignacio Rodriguez Relaño, PhD for your Early Career Investigator awards, I am proud of you!