CRISPR Therapeutics Prices Upsized Convertible Senior Notes Offering CRISPR Therapeutics (Nasdaq: CRSP) priced an upsized private offering of $550 million aggregate principal amount of 2031 convertible senior notes, plus a $50 million initial purchaser option. Closing is expected on March 16, 2026.The notes bear an effective coupon increased to 1.7308% to offset anticipated Swiss withholding, mature on March 1, 2031, and convert at 13.0617 shares per $1,000 (initial conversion price ~$76.56, ~45% premium to the March 10, 2026 share price). Estimated net proceeds are ~$536.3 million (or ~$585.2 million if option exercised).

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CRISPR Therapeutics Announces Proposed Convertible Senior Notes Offering CRISPR Therapeutics (Nasdaq: CRSP) announced a proposed private offering of $350 million aggregate principal amount of convertible senior notes due 2031, with an initial purchaser option of up to $52.5 million. Interest will accrue semiannually beginning September 1, 2026, and notes mature March 1, 2031. Upon conversion, the company will deliver common shares. The company intends to use net proceeds for general corporate purposes. Terms including interest rate and conversion rate will be set at pricing; the notes and shares will not be registered under the Securities Act.

#CRSP CRISPR Therapeutics Announces Proposed Convertible Senior Notes Offering

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Original post on benzinga.com

Cathie Wood's Favorite Biotech Stock Is Under Pressure Amid Insider Sales And Slow Revenue Growth: Momentum Score Drops Swiss-American biotechnology company, CRISPR Therapeutics AG (NASDAQ: CRS...

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[Original post on benzinga.com]

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CRISPR Therapeutics Highlights Strategic Priorities and Anticipated 2026 Milestones -2026 is poised to be a data- and milestone-rich year across the portfolio- -CASGEVY ® launch acceleration continues, supporting multi-billion-dollar potential- -Broad pipeline supported by leading gene-editing and siRNA platforms across cardiovascular, autoimmune, oncology and rare diseases-

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CRISPR Therapeutics Provides Broad Update on Zugocaptagene Geleucel (Zugo-cel; formerly CTX112™) in Autoimmune Diseases and Hematologic Malignancies CRISPR Therapeutics (Nasdaq: CRSP) provided a broad update on zugocaptagene geleucel (zugo-cel), an allogeneic anti-CD19 CAR T, across autoimmune diseases and B-cell malignancies on Dec 22, 2025. Key clinical readouts include deep B-cell depletion and drug-free DORIS remission through Month 6 in an SLE patient at the 100 million cell dose, and in R/R large B-cell lymphoma an ORR 90% and CRR 70% at the 600 million cell RP2D. Safety findings: Grade 3 CRS and ICANS each at 17% and serious infections 8% at the RP2D. A Phase 1 basket study in ITP and wAIHA has started and a collaboration with Lilly will evaluate zugo-cel plus pirtobrutinib. Additional data expected H2 2026.

#CRSP CRISPR Therapeutics Provides Broad Update on Zugocaptagene Geleucel (Zugo-cel; formerly CTX112™) in Autoimmune Diseases and Hematologic Malignancies

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#CRSP CRISPR Therapeutics Provides Business Update and Reports Third Quarter 2025 Financial Results

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CRISPR Therapeutics Announces Positive Phase 1 Clinical Data for CTX310® Demonstrating Deep and Durable ANGPTL3 Editing, Triglyceride and Lipid Lowering -Data presented in a late-breaking presentation at the American Heart Association (AHA) Scientific Sessions 2025- -Phase 1 clinical data for CTX310® demonstrate robust, dose-dependent reductions in circulating ANGPTL3 with a mean reduction from baseline of -73% (maximum -89%), a mean reduction in

#CRSP CRISPR Therapeutics Announces Positive Phase 1 Clinical Data for CTX310® Demonstrating Deep and Durable ANGPTL3 Editing, Triglyceride and Lipid Lowering

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CRISPR Therapeutics and Sirius Therapeutics Announce First Patient Dosed in Phase 2 Trial of SRSD107 for Thromboembolic Disorders in Europe CRISPR Therapeutics (NASDAQ: CRSP) and Sirius Therapeutics have announced the dosing of the first patient in a Phase 2 clinical trial of SRSD107, their co-developed Factor XI (FXI) siRNA therapy for preventing venous thromboembolism in total knee arthroplasty patients.SRSD107 demonstrated promising results in Phase 1 trials, showing over 93% reduction in FXI levels and a twofold increase in aPTT relative to baseline. The treatment's effects were sustained for up to six months post-dosing, suggesting potential for semi-annual administration.The therapy aims to address limitations of current anticoagulants by reducing pathological thrombosis while minimizing bleeding risk. The addressable market includes patients with atrial fibrillation, VTE, cancer-associated thrombosis, and various cardiovascular conditions where bleeding risk currently limits treatment options.

#CRSP CRISPR Therapeutics and Sirius Therapeutics Announce First Patient Dosed in Phase 2 Trial of SRSD107 for Thromboembolic Disorders in Europe

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CRISPR Therapeutics rose in premarket trading after J.P. Morgan initiated coverage with an Overweight rating and a $70 price target.

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Mars, the maker of M&M’s and Skittles, is leveraging CRISPR gene-editing technology to strengthen cocoa production amid global supply challenges.

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CRISPR Therapeutics Provides Business Update and Reports Second Quarter 2025 Financial Results CRISPR Therapeutics (NASDAQ:CRSP) reported its Q2 2025 financial results and business updates, highlighting significant progress across its commercial and clinical programs. The company's flagship product CASGEVY® has achieved its target of activating 75 authorized treatment centers globally, with ~115 patients completing cell collection and 29 receiving infusions.Key clinical developments include CTX310™ showing promising preliminary data with up to 82% reduction in triglycerides and 86% in LDL, and ongoing trials for CTX112™ and CTX131™ in oncology and autoimmune diseases. The company maintains a strong financial position with $1.7 billion in cash and equivalents, despite reporting a net loss of $208.5 million for Q2 2025.

#CRSP CRISPR Therapeutics Provides Business Update and Reports Second Quarter 2025 Financial Results

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