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Huge thanks for your participation in #CSHApandemic! I hope you enjoyed the time in the conference in Awaji island as well as your visit in my lab😁

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Smiling members of the Sato lab, and guests, bend, squat, and pose with two-finger “peace signs” and “thumbs up” in front of a white board wall. One person holds a copy of the journal Cell.

Smiling members of the Sato lab, and guests, bend, squat, and pose with two-finger “peace signs” and “thumbs up” in front of a white board wall. One person holds a copy of the journal Cell.

Huge gratitude to @systemsvirology.bsky.social for organizing #CSHApandemic and bringing us all together, and for including @cp-cell.bsky.social in the program. And also for hosting the coolest lab party in Tokyo! 😎🥼🎉

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And of course loooots more exciting talks, posters and discussions that I don't have time to cover here..

Big thanks to the organisers and everyone who visited Japan for this fantastic conference!

And I'll end with a photo of the beautiful Awaji sunrise from the last day there! 🌅

#CSHApandemic

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And good to see Jonathan Pekar presenting our work on the recency and phylogeography of SARS-CoV and SARS-CoV-2 related viruses!

We've made some exciting additions to this work since our preprint that we hope will be published soon.

In the meantime: www.biorxiv.org/content/10.1...

#CSHApandemic

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Wuhan lab samples hold no close relatives to virus behind COVID Shi Zhengli, the virologist at centre of COVID lab-leak theory, reveals coronavirus sequences from Wuhan institute.

Was great to see Zhengli Shi's presentation (albeit recorded) on years of sarbecovirus sampling in bats found across China! 🦇

Really hope that this data will be made publicly available soon!

Some more details here: www.nature.com/articles/d41...

#CSHApandemic

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Sick animals suggest COVID pandemic started in Wuhan market A preliminary analysis takes a closer look at genomic data collected at the market.

@angierasmussen.bsky.social presented a newsworthy deep dive on the Huanan market environmental sample transcriptomic data. Showing that signals of CoV-like infection was present for a number of the animals in the market.

reported by Nature news here: www.nature.com/articles/d41...

#CSHApandemic

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Mapping glycoprotein structure reveals Flaviviridae evolutionary history - Nature Combined phylogenetic analyses and glycoprotein structure prediction across the Flaviviridae reveals divergent membrane fusion systems and provides insights into the complex evolutionary history withi...

@eddieholmes.bsky.social gave a tour de force on virus discovery and evolution!

Showcasing our work on Flaviviridae glyco evolution with @jonathonmifsud.bsky.social & @grovearmada.bsky.social

www.nature.com/articles/s41...

+work on segmented CoVs I can't wait to get my hands on! 👀

#CSHApandemic

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Yusuke Kosugi showed his ongoing work on determining which spike substitutions are responsible for host tropism broadness across the sarbecoviruses! 🦇🦠

Stay tuned for this one!

#CSHApandemic

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Jumpei Ito presented on using pLMs to predict SARS-CoV-2 variant fitness using only the Spike protein sequence. 🤖🧬

Read up on the CoVFit model in our preprint: www.biorxiv.org/content/10.1...

#CSHApandemic

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@jarelelgin.bsky.social gave a fantastic talk on his work about the recombination even which led to MERS-CoV's DPP4-using RBD. 🦇🐫

Read the paper here: virologyj.biomedcentral.com/articles/10....

and more work on this area coming soon! 👀

#CSHApandemic

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I got the chance to present a fun, ongoing project on the evolution of the seasonal human CoV NL63.

If you're working on this - sometime forgotten - little virus do give me a shout! trying to expand this project as much as we can!

#CSHApandemic

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A busy number of weeks have ended with the #CSHApandemic conference held in the Awaji island 🏝️!

Was amazing to see so many CoV experts in one place and discuss exciting science!

Here's a little 🧵on findings presented at the conference from our lab and others to look out for in the new year!

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Beyond honored to present on the pandemic potential of MERS and MERS-related viruses through recombination at this prestigious conference! Standing among giants in virology was truly inspiring (and excitedly anxious)! Thankful for the insightful discussions! #CSHApandemic

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Wonderful meeting was over.
The coronavirologists got together, and I heard many fascinating talks. #CSHApandemic

I'm glad I can ask questions and talk directly to authors who developed amazing virus research that I was impressed by when I read their papers in the past.

Please visit Japan again🇯🇵

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"A number of participants at #CSHApandemic were good enough to apologise today and yesterday for the behaviour of Greg Towers and @angierasmussen.bsky.social on tuesday night. Much appreciated. Some younger virologists told me it made them question their career choice." - Jonathan Latham

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Obvious issue with Angela Rasmussen's #CSHApandemic presentation about infected animals at Huanan Seafood Market is Bloom’s Figure 3 shows a positive correlation between raccoon dog DNA and reads for bamboo rat CoV, canine CoVs, and rabbit CoV—but a negative correlation with SARS2.
t.co/Pr6QqQko4O

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Last day at #CSHApandemic ! I am biased 😉, but two beautiful talks today by @jollylab.bsky.social and Greg Towers...and so many other fascinating talks! Lots to think about!

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Contrast Ralph Baric’s talk #CSHApandemic on emerging virus threats with the Global Virome Project in 2017. Now accidental and/or intentional release isn't on the radar? This field continues to demonstrate it's too conflicted to regulate itself or investigate COVID-19 origins.

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First full day of #CSHApandemic ! A fantastic line up so far. We've been hearing about some great CoV science!

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In the coming days, our international #CSHApandemic meeting, organized by Cold Spring Harbor Asia, will finally kick off in Awaji, Japan🇯🇵 Super excited and honored to be the local organizer of this fantastic meeting. Looking forward to seeing great COVID scientists😆‼️

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