Words on back of nondescript building poorly edited to say “Happiness is submission to JACS”.

Thank you @sarponggroup.bsky.social #ChemCollabs

Flier for Chemistry and Food Tuesdays

Join Chemistry & Food Tuesdays tomorrow with guest, Daniel Corey, Ph.D. (Fehl Lab alum). Daniel’s talk will focus on the importance of collaboration and community in science. #wsuchemistry #chemcollabs #chemtalk

See you there ⬇️
Tuesday, February 18th, 12:30-1:30 pm, room 111, Chemistry

The 2H-tautomer of indazole absorbs light more strongly than the 1H-tautomer at longer wavelengths
#ChemSky #chemcollabs

Starting off 2025 pretty well - new #ChemCollabs paper about to hit #ChemRxiv with a pretty cool new reaction under optimization
And some neat chemistry on [REDACTED] project
And the @organicdivision.org ORGN program for #ACSSpring2025 is going to be excellent!

Cross-Coupling Reactions with Nickel, Visible Light, and tert-Butylamine as a Bifunctional Additive Transition metal catalysis is crucial for the synthesis of complex molecules, with ligands and bases playing a pivotal role in optimizing cross-coupling reactions. Despite advancements in ligand desig...

Tert-butylamine as a labile ligand and base enables cross-coupling reactions with various nucleophile classes. A great collaboration of Jonas with the Sigman lab and Gschwind group
#ChemSky #ChemCollabs #photocatalysis

doi.org/10.1021/acsc...

Ni-Catalyzed Enantioselective Desymmetrization: Development of Divergent Acyl and Decarbonylative Cross-Coupling Reactions Ni-catalyzed asymmetric reductive cross-coupling reactions provide rapid and modular access to enantioenriched building blocks from simple electrophile precursors. Reductive coupling reactions that ca...

This divergent cross coupling paper in #JACS from @reiswoman.bsky.social Reisman lab @CalTech with the Sigman lab @ Utah with #Amgen is really neat
Differential coupling products from anhydrides - nice #ChemCollabs work everyone

Carbon quaternization of redox active esters and olefins by decarboxylative coupling The synthesis of quaternary carbons often requires numerous steps and complex conditions or harsh reagents that act on heavily engineered substrates. This is largely a consequence of conventional pola...

10/ #12DaysofPapers #ChemSky
Presenting some of my favorite #PfizerChemistry papers from 2024
Next up is a multi-center #ChemCollabs from our Groton and La Jolla labs with @shenvi.bsky.social, the Baran lab and #Biogen out in @science.org forming tertiary sp3 centers from RAEs or olefins

Computational Methods Enable the Prediction of Improved Catalysts for Nickel-Catalyzed Cross-Electrophile Coupling Cross-electrophile coupling has emerged as an attractive and efficient method for the synthesis of C(sp2)–C(sp3) bonds. These reactions are most often catalyzed by nickel complexes of nitrogenous liga...

4a/ #12DaysofPapers #ChemSky. This 2024 favorite is a #PfizerChemistry collab with the Weix (Wisconsin) and Sigman (Utah) labs towards computationally designed ligands for Ni-catalyzed cross electrophile coupling. Improvements in selectivity up to 300% #ChemCollabs

2/n #12DaysofPapers #ChemSky I’m a big fan of S(VI) and excited to see the #ChemCollabs continue between #PfizerChemistry and the Willis Lab @rhpdcu.bsky.social at Oxford including this facile Cu-catalyzed access to sulfinates using SMOPS - one of the best reagent names pubs.acs.org/doi/10.1021/...

A metal-free strategy to construct fluoroalkyl–olefin linkages using fluoroalkanes We present a metal-free strategy to access fluoroalkyl–olefin linkages from fluoroalkane precursors and vinyl-pinacol boronic ester (BPin) reagents. This reaction sequence is templated by the boron re...

1/n - #12DaysofPapers
Highlighting this #PfizerChemistry #ChemCollabs with the Szymczyk Lab @ Michigan Chem enabling C-H coupling of fluoroalkyls with vinyl-BPins to access some really neat complex fragments ready for additional functionalization
pubs.rsc.org/en/content/a...