Thanks to many co-authors from our group, including #ZoranGajic (former MD-PhD & computational genomics star), #ChristinaCaragine, #XiaoWang, @rachelyan.bsky.social , #HarmWessels & #CongyiLu.

A special shout-out to #MatLegut, #JamesKim & #NeilBapodra who launched this project many years ago! 🙏

To test this, Xinhe & lab 3D genome guru 👩‍🔬 #ChristinaCaragine performed enhancer HiChIP and found that many of the PD-L1 CREs that we validated individually contact the promoter of PD-L1 or the promoter of a nearby PD-L1 regulator (JAK2).