How does #cladribine treatment affect disease activity in people with highly active #MultipleSclerosis?

Klaus Schmierer and colleagues provide the 2-year results from the MAGNIFY-MS Study:
journals.sagepub.com/doi/10.1177/...

📄New research online!

💊What is the real-world effectiveness of #cladribine tablets in people with #MultipleSclerosis?

👨‍⚕️Matteo Lucchini and colleagues analyzed data from multiple centers in Italy:
journals.sagepub.com/doi/full/10....

#Mavenclad 's first cycle left me with a feeble immune system. I can't work (at the hospital during flu season), and I spent Christmas and New Year's Eve appart from my family.
But if my dog ​​wants to share my bed and sleep at my feet, I'm fine with that. 🐶 🧡 😷
#MS #MStalks #MSsucks #cladribine

#cladribine sucks

Early Promise, Later Challenges With Cladribine for MS Cladribine is linked to lower risk for disability progression in patients with relapsing-remitting multiple sclerosis vs S1PRMs, at least in the short term, a study shows.

#MS
#Mavenclad
#Cladribine

#SEP pas la panacée 🤔

👇👇

www.medscape.com/viewarticle/...

My birthday gift is #cladribine, #Mavenclad. Not sure what to expect. #MSsucks

🧪 Long-term study of #Cladribine in #MultipleSclerosis shows no loss of humoral immunity after up to 7 years. Patients maintained protective IgG to common pathogens & mounted new responses (e.g. SARS-CoV-2). Supports strong long-term safety profile.

journals.sagepub.com/doi/epdf/10....

Cladribine Is Associated With Stable Cortical Gray Matter Lesion Burden in Multiple Sclerosis: A 7T MRI Study
onlinelibrary.wiley.com/doi/10.1111/...

#neuroimaging #neurology #neuroskyence #radiology #cladribine #multiplesclerosis #7TMRI #corticallesions

MS patients in England to benefit from major roll out of take-at-home pill Cladribine tablet for those with active multiple sclerosis will reduce hospital visits and free up appointments

#MS patients in England to benefit from major roll out of take-at-home pill. #Cladribine tablet for those with active multiple sclerosis will reduce hospital visits and free up appointments, by @andrewgregory.com www.theguardian.com/society/2025... via @theguardian.com

As someone with #MS on #Cladribine this is a very promising study.

A ceramic cup with a kookaburra on the inner rim. Inside are two round tablets.

Woohoo last of year two month one #MS chemo drugs. Only one more month to go and hopefully no more ever.

#MultipleSclerosis #Mavenclad #Cladribine

Question: theoretically, is there a mechanism by which CD20 #MS #DMT #mAB #Kesimpta could stop #PASC neuroinflammation of ten months duration?

Or #cladribine #mavenclad?

What is expressed by the activated neutrophils that might respond in a patient with a pre-existing poor BBB?

Cladribine Triphosphate - an overview | ScienceDirect TopicsScienceDirect

#cladribine, a pro-drug, to its active metabolite. It uses #deoxycytodinekinase to produce cladribine tri-phosphate, the active drug. www.sciencedirect.com/topics/medic...

What is the cofactor for dCK? #magnesium

All my magnesium deficit symptoms roared back week 1 #Mavenclad … 🧵

Any other #MultipleSclerosis sufferers out there on #Mavenclad / #Cladribine?
I took it June/July 2021/22.
I'm doing great. Just wish my neurologist could give me a definite plan. It's so frustrating. That's my undiagnosed Autism for you!

Mavenclad label now extended in UK to treat active relapsing MS The U.K.'s regulatory agency is the first in Europe to extend the indication of Mavenclad to include adults with active relapsing forms of MS.

Jetzt sollte die EMA nachziehen. #Cladribine

multiplesclerosisnewstoday.com/news-posts/2...