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This new systematic review investigates whether gonadotrophin-releasing hormone agonist pretreatment has a positive effect on pregnancy outcomes in women with adenomyosis who were undergoing a frozen embryo transfer cycle.

doi.org/10.1016/j.rb...

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In this new Commentary article, former RBMO Chief Editor, Bart Fauser and Arie Franx outline how current outcome measures could detrimentally affect the way ART is practiced, and propose ways to improve such outcomes.

doi.org/10.1016/j.rb...

#ClinicalAssistedReproductiveTechnology #ARToutcomes

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This large multicenter cohort study indicated that between frozen embryo transfer (FET) may reduce the risk of monozygotic twinning (MZT) at the blastocyst stage.

doi.org/10.1016/j.rb...

#ClinicalAssistedReproductiveTechnology #Blastocyst

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This new narrative review examines the physiological and pathological roles of E2 in natural and ART cycles, emphasizing its impact on endometrial function, implantation, and pregnancy outcomes.

doi.org/10.1016/j.rb...

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A paper demonstrating that critical thinking and open debate are essential not only to science but also to improving the care we provide our patients.

Read the Commentary for free from issue 51.2

doi.org/10.1016/j.rb...

#RBMOcommentary #ClinicalAssistedReproductiveTechnology #PeerReview

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This new review article compiles the literature on embryological-clinical classifications into a new system that more adequately defines all published female genitourinary malformations into six groups of anomalies

doi.org/10.1016/j.rb...

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The data presented in this paper suggest that progesterone priming may positively influence oocyte donation cycles while potentially offering a more patient-friendly and cost-effective option for donors.

doi.org/10.1016/j.rb...

#ClinicalAssistedReproductiveTechnology #OocyteDonation

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Published open access, this new study proposes a hypothetical mechanism through which progestin indirectly affects oocyte development, leading to a compensatory increase in mitochondrial gene expression in mGCs.

doi.org/10.1016/j.rb...

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The data presented in this new study supports the continued use of aromatase inhibitors for gonadotoxic treatment cycles, as IVF cycle outcomes and live birth rates are comparable to those for cycles with no adjuvant medication.

doi.org/10.1016/j.rb...

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Given its shorter testing duration and potential to improve pregnancy outcomes, using library concentration to guide the transfer priority of embryos in fresh cycles could be considered.

doi.org/10.1016/j.rb...

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poster for the RBMOnline article, with photo of lead author Isotta Magaton in clinical coat, and background image of a box and whisker chart from the paper.  The article is  'Oocyte retrieval of few follicles does not require analgesia: a large-scale multicentre pain analysis', authored by Isotta Magaton, Martina Nordin, Ikbale Siercks, Roxana Popovici, Eva Boogen, Stefan Eisenhardt, Cosima Huober-Zeeb, Jan-Simon Lanowski, Roumet Marie, and Michael von Wolff.

“The median pain intensity is only mild (3.0 on a scale of 0 to 10) if one or few follicles are aspirated without anaesthesia and analgesia, the pain intensity does not increase with repetitive aspirations and the complication rate is very low. Therefore, repetitive oocyte pick-ups can easily performed without anaesthesia and analgesia to reduce time and costs.”

poster for the RBMOnline article, with photo of lead author Isotta Magaton in clinical coat, and background image of a box and whisker chart from the paper. The article is 'Oocyte retrieval of few follicles does not require analgesia: a large-scale multicentre pain analysis', authored by Isotta Magaton, Martina Nordin, Ikbale Siercks, Roxana Popovici, Eva Boogen, Stefan Eisenhardt, Cosima Huober-Zeeb, Jan-Simon Lanowski, Roumet Marie, and Michael von Wolff. “The median pain intensity is only mild (3.0 on a scale of 0 to 10) if one or few follicles are aspirated without anaesthesia and analgesia, the pain intensity does not increase with repetitive aspirations and the complication rate is very low. Therefore, repetitive oocyte pick-ups can easily performed without anaesthesia and analgesia to reduce time and costs.”

This open access paper investigates the pain intensity of oocyte retrieval without anaesthesia, discussing techniques which may save costs and treatment time, and may also reduce anxiety in patients who are afraid of anaesthesia.

doi.org/10.1016/j.rb...

#ClinicalAssistedReproductiveTechnology

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This new review article compiles the literature on embryological-clinical classifications into a new system that more adequately defines all published female genitourinary malformations into six groups of anomalies

https://doi.org/10.1016/j.rbmo.2024.104751

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