Molecular mechanism of menthol-induced TRPV5 channel inhibition - Nature Communications TRPV5 ion channels play pivotal roles in epithelial physiology. Here, the authors describe that the common compound menthol acts as a pore blocker on these channels and provide a functional and struct...

Congratulations to León Islas's and Vera Moiseenkova-Bell's lab members!!! Angélica Méndez-Reséndiz and José De Jesús-Pérez did amazing job on discovering how menthol inhibits TRPV5 channel. #cryoEM #TRPV #menthol #ColdSensation #ion #channels #calcium
www.nature.com/articles/s41...

Uncovering the Mystery Behind Cold Sensation and Menthol’s Cooling Effect Researchers have solved a decades-old mystery about how the body senses cold — and why menthol feels cool — paving the way for new treatments for pain, migraines, and dry eyes.

Uncovering the Mystery Behind Cold Sensation and Menthol’s Cooling Effect #Science #Biology #Neurobiology #ColdSensation #Menthol

www.discovermagazine.com/uncovering-the-mystery-b...

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Visit the #BPS2026 #Newsroom! Learn the science behind #TuberculosisBacteria #NewMicroscopyTechnqies #mRNAVaccines #ZeroGravityMicrscopes #ColdSensation #ItchRegulators #stereocilia and #hearingloss