A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID — Kumar et al. "We also defined a distinct circulating CD14⁺ monocyte state (LC-Mo) associated with LC […] showed increased TGFβ/WNT–β-catenin signaling that increased over time and exhibited interindividual variability."

From Germany:

A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID

www.nature.com/articles/s41...

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#LongCovid #CovidLung

Frontiers | Interrogating pulmonary diffusing capacity in long COVID: insights from DLCO and DLNO testing IntroductionThe lingering respiratory effects of COVID-19, particularly in patients with Long COVID, remain poorly understood, prompting a comprehensive eval...

Interrogating pulmonary diffusing capacity in long COVID: insights from DLCO and DLNO testing

www.frontiersin.org/journals/phy...

"between group analysis revealed that only in females, not in males, was DLNO and Vc significantly lower in those with LC"

#LongCovid #CovidLung

Longitudinal assessment of pulmonary perfusion and ventilation defects in long COVID: A one-year study using phase-resolved functional lung (PREFUL) MRI — Ouyang et al. "We found ventilation defects normalizing by six months, while perfusion defects persisted for up to one year. Severe perfusion defects at the acute phase were associated with a higher risk of long COVID, persistent dyspnea, and fatigue."

From China

Longitudinal assessment of pulmonary perfusion and ventilation defects in long COVID

www.sciencedirect.com/science/arti...

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#LongCovid #Covidlung

Clinical, Radiographic, and Physiological Correlates of Post-COVID-19 Dyspnea in Military Health System Beneficiaries: Results From the Chronic Impairment With Pulmonary Symptoms (ChIPS) Sub-study — Goertzen et al. "Overall, this study demonstrates both subjective and objective differences between those with ongoing dyspnea following COVID-19 infection that are not explained by standard investigations typically ordered in clinical care for chronic dyspnea."

From the US

Clinical, Radiographic, and Physiological Correlates of Post-COVID-19 Dyspnea in Military Health System Beneficiaries

dx.doi.org/10.1093/ofid...

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#LongCovid #Covidlung

Psalm 20:7 "Some trust in chariots and some in horses, but we trust in the name of the LORD our God."

God can heal you straight up!

#running #covidlung #afib #healing #praisethelord

News Release 30-Apr-2025 Long COVID biomarkers found – associated with respiratory problems Peer-Reviewed Publication Karolinska Institutet Researchers at Karolinska Institutet have identified biomarkers in the blood associated with symptoms of long COVID, particularly severe respiratory disorders. The discovery can pave the way for future diagnosis and treatment. The results are published in the top-ranking scientific journal Nature Immunology. Long COVID, also known as Post COVID, is a condition characterised by persistent symptoms of previous COVID-19. A new study from Karolinska Institutet, Sweden, and Cardiff University, UK, led by Marcus Buggert, docent at the Department of Medicine, Karolinska Institutet (Huddinge), has identified a set of proteins in the blood of people with Long COVID. “The proteins were mainly found in patients with Long COVID and severe respiratory problems,” says Dr Buggert. “This is a biomarker pattern that we know to be linked to inflammatory signal pathways involved in cell death and lung damage and that has also been observed in other patient groups with severe pulmonary disorders.”

News Release 30-Apr-2025
"Long COVID biomarkers found – associated with respiratory problems"
www.eurekalert.org/news-release...

Research paper:
"Identification of soluble biomarkers that associate with distinct manifestations of long COVID"
www.nature.com/articles/s41...

#LongCovid #CovidLung

Had a #LongCovid #CovidLung attack tonight. I forgot to take my #Symbicort this morning, and it came back to bite me.
Thankfully, the symptom was being unable to catch my breath, and nothing much worse; apart from the mini panic attack that came after.

2/

"We also assessed lung parenchymal involvement at chest CT. More than two thirds of patients showed CT abnormalities, such as fibrotic alterations or persisting ground grass opacities, among both in- and out-patients."

#CovidLung #PostCovid19 #PwLC