Ni-catalyzed asymmetric reductive #CrossCoupling 🔥Using a Ni/Biox platform, this method by Qiu & Gong delivers enantioenriched tertiary α-aryl acetals/ketals with steric/electronic effects guiding selectivity✨
#nickel
👉 buff.ly/oyklRSp
🔔Issue 5 is available! Please read the cover article:
Electrochemically driven reductive coupling of nitroarenes with alkyl bromides by Jiayu Mo 𝘦𝘵 𝘢𝘭.
#Electrochemistry #OrganicSynthesis #CrossCoupling
#Free_to_read
🔗https://doi.org/10.1039/D5QO01269D
Bicyclo[1.1.1]propellane reactivity unlocked🚀 Vasudevan Dhayalan reviews organolithium, Mg, Zn & B-mediated strain-release functionalization⚗️ Mild, regioselective, eco-friendly methods deliver diverse BCPs & amine scaffolds✨
#CrossCoupling
👉 buff.ly/yoME2Sa
Transition metal-free #CrossCoupling 🚀 Alkyl fluorides + #Organolithiums react under mild heat with liquid-assisted stirring w/o expensive catalysts🔥 Tolerates 3° fluorides & diverse functional groups🧪 This breakthrough by Wolf & co-workers could reshape TM-free coupling chemistry
👉 buff.ly/tWFwGiw
First nickel-catalyzed reductive #CrossCoupling of aldehydes & alkenyl halides🚀 Takuya Kurahashi report a stereoconvergent route to allyl alcohols🌟 Enabled by silyl activation & polarity inversion, this strategy tackles a long-standing challenge in synthesis🧪
#nickel
👉 buff.ly/86v9fyB
Dive into the world of substituted alkynes🚀 From #diynes to #enynes, our review by Janine Cossy explores the latest in chemo- & stereoselective C–C bond formation via alkynyl #CrossCoupling, powered by affordable Mn, Fe, Co, Ni & Cu catalysts🔬
#catalysis
👉 buff.ly/YYAbvj5
Discover the potential of migratory #CrossCoupling for repurposing coupling partners🧪The latest work by Richard Liu and co-workers explores this, while also tackling ortho-isomerization and nucleophile scope. #Palladium #Catalysis
👉 thieme-connect.de/products/ejo...
🔬 One of SynOpen’s most cited articles of 2023/2024!
Explore a decade of transition-metal-catalyzed cross-coupling reactions in this comprehensive review by Anil Kumar & team — from Pd to Fe, Ni & beyond!
👉 www.thieme-connect.com/products/ejo...
#CrossCoupling #Catalysis #Organometallics
Want to build complex molecules? 🏗️ All-carbon #quaternarycenters are a key building block, but their synthesis remains tricky 🧪 Learn about the new advances in #transitionmetal-catalyzed C(sp³)–C(sp³) #crosscoupling reactions in our review by Shou-Fei Zhu
👉 https://buff.ly/4ht8SJS
Jie Zhao unveils a revolutionary method for coupling #ethers using light-activated #zirconium. This opens doors for efficient C(sp³)-C(sp³) bond formation with ✨High Selectivity & ✨Broad Functional Group Tolerance
#catalysis #crosscoupling
👉 www.thieme-connect.com/products/ejo...
