Three active-site fragments obtained from a cystallographic fragment screen of Bacillus subtilis CdaA were used in an silico drug-repurposing screen that identified a drug with inhibitory potential #CdaA #CyclicDiAMP #FragmentScreening t.co/heUH3ZLcj1

A crystallographic fragment screen against CdaA from Listeria monocytogenes provides potential starting points for the development of antibiotics against several CdaA-dependent bacteria. #FragmentScreening #CdaA #CyclicDiAMP t.co/Xg5ZpZjaJH