A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs

Our #BaseEditing paper is DG-GT’s “Paper of the Quarter”! 🎉

We used precise gene editing to correct cancer mutations in TP53 – and watched as corrected cells nearly vanished. A step toward mRNA therapies for cancer! 💡

Full paper: rdcu.be/exqtH #CancerResearch #GeneEditing #Science #DG_GT