Op de Belg is toch alles beter. Qua sport 😝 #enZap

I do agree that there needs to be a very good reason to bring new (=expensive) and additionally toxic treatments early in the course. Cannot justify if you get the same benefit by sequential use. This trial #ENZAp focussed on pts at high risk of enza failure; addition of LuPSMA mitigated that.

🚨Online today: Prognostic and predictive value of baseline PSMA-PET total tumour volume and SUVmean in metastatic castration-resistant #prostatecancer in #ENZAp (ANZUP1901): a substudy from a multicentre, open-label, randomised, phase 2 trial

www.thelancet.com/journals/lan...

Congrats @anzuptrials.bsky.social #ENZAp @thelancetoncol.bsky.social‬ publication by Prof Emmett @ascocancer.bsky.social #Movember #CancerAustralia #Astellas #ARTnet #StVincentsClinic #RoyMorgan #Novartis #MimSoftware #GenesisCare #ANSTO #NHMRCCTC @profiand.bsky.social
anzup.org.au/wp-content/u...

Congrats @anzuptrials.bsky.social #ENZAp study oral presentation by Prof Emmett @ascocancer.bsky.social #ASCO25 #Movember #CancerAustralia #Astellas #ARTnet #StVincentsClinic #RoyMorgan #Novartis #MimSoftware #GenesisCare #ANSTO #NHMRCCTC @profiand.bsky.social

Congrats @anzuptrials.bsky.social #ENZAp study +ve OS & QoL results presented by Prof Emmett @ascocancer.bsky.social #GU25 & in @thelancet.bsky.social #Movember #CancerAustralia #Astellas #ARTnet #StVincentsClinic #RoyMorgan #Novartis #MimSoftware #GenesisCare #ANSTO #NHMRCCTC @profiand.bsky.social

The @anzuptrials.bsky.social #ENZAp trial outcome presented by Prof Louise Emmett today. #enzalutamide +/- #LuPSMA good news for
#prostatecancer #survival #qualityoflife #cancerresearch #prostate @thelancet.bsky.social

OS HR 0.549

Deterioration-free survival HR about 0.5

Better QoL

Conclusions; Better OS in people at risk of poorer outcomes with enza alone 8mo OS benefit Better QoL

Beautiful presentation by Prof Louise Emmett of the @anzuptrials.bsky.social #ENZAp trial of enzalutamide +/- LuPSMA:
✅ Improved OS
✅ Improved quality of life

Published today in Lancet Oncology www.thelancet.com/journals/lan...

Excited for Prof Louise Emmett presenting #ENZAp today at #GU25 on behalf of @anzuptrials.bsky.social @ascocancer.bsky.social