Glycaemic, appetite and circadian benefits of a dairy-enriched diet with high-protein breakfast and early daytime-restricted carbohydrate intake in type 2 diabetes: a randomised crossover trial - Diab... Aims/hypothesis The circadian timing of food intake and the composition of dietary protein sources may jointly influence metabolic regulation. Our aim was to examine the effects of a dairy-enriched vs...

Up front and free to read in our April issue #editorspicks: Glycaemic, appetite and circadian benefits of a dairy‑enriched diet with high‑protein breakfast and early daytime‑restricted carbohydrate intake in type 2 diabetes link.springer.com/article/10.1...

Islet amyloid disrupts MHC class II antigen presentation and delays autoimmune diabetes in NOD mice - Diabetologia Aims/hypothesis Islet amyloid contributes to beta cell failure in type 2 diabetes through several mechanisms, one being the potent induction of local islet inflammation through activating inflammatory...

Up front and free to read in our April issue #editorspicks: Islet amyloid disrupts MHC class II antigen presentation and delays autoimmune diabetes in NOD mice doi.org/10.1007/s001...

Effects of combined intraduodenal administration of lauric acid and l-tryptophan on postprandial plasma glucose, glucoregulatory hormones and gastric emptying in type 2 diabetes: a double-blind, rando... Aims/hypothesis In healthy men, lauric acid (C12) and l-tryptophan (Trp), when administered intraduodenally in loads of 1.26 and 0.42 kJ/min (0.3 and 0.1 kcal/min), respectively, that are individually...

Up front and free to read in our April issue #editorspicks: Effects of combined intraduodenal administration of lauric acid andl‑tryptophan on postprandial plasma glucose, glucoregulatory hormones and gastric emptying in type 2 diabetes doi.org/10.1007/s001...

The evolving understanding of cystic fibrosis-related diabetes in the highly effective modulator therapy era: a scoping review - Diabetologia Cystic fibrosis-related diabetes (CFRD) is a unique form of diabetes that shares features with both type 1 and type 2 diabetes and is most often characterised by transient postprandial hyperglycaemia ...

Up front and free to read in our April issue #editorspicks: The evolving understanding of cystic fibrosis-related diabetes in the highly effective modulator therapy era: a scoping review doi.org/10.1007/s001...

Sex steroids, SHBG and type 2 diabetes in women: what do we really know? - Diabetologia Androgens and oestrogens differentially regulate metabolic processes that impact the development of type 2 diabetes in women. The biological actions of these sex steroids are, however, dependent on th...

Up front and free to read in our April issue #editorspicks: Sex steroids, SHBG and type 2 diabetes in women: what do we really know? doi.org/10.1007/s001...

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Ten reviews handpicked by the Choice editors from the recent issue of Choice Magazine. These #EditorsPicks stand out for their excellence, timeliness, originality, or sheer reading pleasure.
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Ketone supplementation dose-dependently lowers postprandial blood glucose, lipid and ghrelin levels in individuals with type 2 diabetes: a randomised crossover study - Diabetologia Aims/hypothesis Postprandial hyperglycaemia and hyperlipidaemia are independent risk factors for CVD in individuals with type 2 diabetes. We aimed to test whether a ketone monoester (KE) and ketone sa...

Up front & free to read in our March issue #editorspicks: Ketone supplementation dose‑dependently lowers postprandial blood glucose, lipid and ghrelin levels in individuals with type 2 diabetes: a randomised crossover study doi.org/10.1007/s001...

MNX1 prevents somatostatin expression in human beta cells by repressing PERCC1 - Diabetologia Aims/hypothesis A highly specific mosaic transcriptional environment guides the fate of pancreatic progenitors during development and maintains the identity of mature endocrine cells. In mice, one suc...

Up front & free to read in our March issue #editorspicks: MNX1 prevents somatostatin expression in human beta cells by repressing PERCC1 doi.org/10.1007/s001...

Up front in the March issue of @diabetologiajnl.bsky.social #editorspicks #diabetesresearch

Up front in the March issue of @diabetologiajnl.bsky.social #editorspicks #diabetesresearch

Impact of cardiovascular autonomic neuropathy on cardiopulmonary, sympathoadrenal and metabolic responses to physical exercise in adults with type 1 diabetes - Diabetologia Aims/hypothesis The aim of this work was to compare the cardiopulmonary, sympathoadrenal and metabolic responses to physical exercise in adults with type 1 diabetes with or without cardiovascular auto...

Up front & free to read in our March issue #editorspicks: Impact of cardiovascular autonomic neuropathy on cardiopulmonary, sympathoadrenal and metabolic responses to physical exercise in adults with type 1 diabetes doi.org/10.1007/s001...

Fully closed-loop systems: can people with type 1 diabetes just do it? Insights from open-source systems - Diabetologia Automated insulin delivery (AID) systems have significantly advanced diabetes management, progressively reducing user interactions required for optimal glucose management. This review evaluates the cu...

Up front & free to read in our March issue #editorspicks: Fully closed‑loop systems: can people with type 1 diabetes just do it? Insights from open‑source systems doi.org/10.1007/s001...

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Improving medication adherence in type 2 diabetes: strategies for better clinical and economic outcomes - Diabetologia Medication adherence is critical for optimal glycaemic management and the prevention of complications in type 2 diabetes mellitus. Despite its importance, non-adherence remains a prevalent issue, with...

Up front & free to read in our March issue #editorspicks: Improving medication adherence in type 2 diabetes: strategies for better clinical and economic outcomes doi.org/10.1007/s001...

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Nine reviews handpicked by the Choice editors from a recent issue of Choice Magazine. These #EditorsPicks stand out for their excellence, timeliness, originality, or sheer reading pleasure.
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Precision medicine in type 2 diabetes: targeting SGLT2 inhibitor treatment for kidney protection - Diabetologia Aims/hypothesis Current guidelines recommend use of sodium–glucose cotransporter-2 inhibitors (SGLT2 inhibitors) for kidney protection in people with type 2 diabetes and early-stage chronic kidney dis...

Up front & free to read in our Feb issue #editorspicks: Precision medicine in type 2 diabetes: targeting SGLT2 inhibitor treatment for kidney protection doi.org/10.1007/s001...

Safety and pharmacokinetics of teplizumab in children less than 8 years of age with stage 2 type 1 diabetes - Diabetologia Aims/hypothesis Teplizumab is approved in the USA and seven other countries to delay stage 3 type 1 diabetes onset in individuals ≥8 years of age with stage 2 type 1 diabetes. As part of a US Food and...

Up front & free to read in our Feb issue #editorspicks: Safety and pharmacokinetics of teplizumab in children less than 8 years of age with stage 2 type 1 diabetes doi.org/10.1007/s001...

Effectiveness of video consultations in type 1 diabetes patients treated with insulin pumps in the outpatient clinic: a randomised controlled trial - Diabetologia Aims/hypothesis The aim of this work was to assess the effect of video consultations over 1 year compared with usual care for patients with type 1 diabetes treated with insulin pumps, with time in ran...

Up front & free to read in our Feb issue #editorspicks: Effectiveness of video consultations in type 1 diabetes patients treated with insulin pumps in the outpatient clinic: a randomised controlled trial doi.org/10.1007/s001...

Comparative physiology and biomimetics in metabolic and environmental health: what can we learn from extreme animal phenotypes? - Diabetologia This review explores the remarkable metabolic adaptations of species that thrive in extreme environments, providing insights into their resilience, flexibility and disease resistance. Species such as ...

Up front & free to read in our Feb issue #editorspicks: Comparative physiology and biomimetics in metabolic and environmental health: what can we learn from extreme animal phenotypes? doi.org/10.1007/s001...

Bridging the variant-to-function gap in type 2 diabetes: advances and challenges - Diabetologia Type 2 diabetes is a polygenic, heterogeneous disease affecting over 530 million individuals worldwide, a number projected to rise to 1.3 billion by 2050. Genome-wide association studies have identifi...

Up front & free to read in our Feb issue #editorspicks: Bridging the variant-to-function gap in type 2 diabetes: advances and challenges doi.org/10.1007/s001...

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@ponnsara.bsky.social spotlights the @rcphysicians.bsky.social Harveian Oration 2025 by Prof John Feehally

Nephrology 1950–2000: An exciting journey from birth to maturity ⏩

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Chiu et al reignite the debate on the utility of metabolic syndrome for cardiovascular risk prediction ↩️

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Ten reviews handpicked by the Choice editors from the January issue of Choice. These #EditorsPicks stand out for their excellence, timeliness, originality, or sheer reading pleasure.
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Andrew Duncombe highlights new analysis showing NHS waiting lists would need to halve for 92% of patients to start elective treatment within 18 weeks.

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Read the article 🔗: www.sciencedirect.co...

Up front & free to read in our January issue #editorspicks: Improved wound healing by dual inhibition of miR‑146a‑5p and miR‑29a‑3p supports a network action of dysregulated miRNAs in diabetic skin link.springer.com/article/10.1...

Shared and distinct metabolomics profiles associated with microvascular complications in the Diabetes Prevention Program Outcomes Study - Diabetologia Aims/hypothesis The aim of this study was to identify shared and distinct metabolite profiles prospectively associated with nephropathy, retinopathy and neuropathy at 15 years’ follow-up among 1947 pa...

Up front & free to read in our January issue #editorspicks: Shared and distinct metabolomics profiles associated with microvascular complications in the Diabetes Prevention Program Outcomes Study doi.org/10.1007/s001...

Persistent C-peptide secretion is associated with favourable CGM metrics in adults with type 1 diabetes - Diabetologia Aims/hypothesis Residual endogenous insulin secretion, reflected by measurable C-peptide, has been linked to improved glycaemic management in type 1 diabetes. We aimed to assess the relationship betwe...

Up front & free to read in our January issue #editorspicks: Persistent C‑peptide secretion is associated with favourable CGM metrics in adults with type 1 diabetes doi.org/10.1007/s001...

Up front in @diabetologiajnl.bsky.social January issue #editorspicks #DiabetesResearch

Up front in @diabetologiajnl.bsky.social January issue #editorspicks #DiabetesResearch

Pharmacological therapies for type 2 diabetes: future approaches - Diabetologia Despite the availability of at least nine differently acting classes of glucose-lowering agents, many people with type 2 diabetes do not achieve or maintain sufficiently tight glycaemic control to avo...

Up front & free to read in our January issue #editorspicks: Pharmacological therapies for type 2 diabetes: future approaches doi.org/10.1007/s001...