#MetaplasticBreastCancer

N=102, 63 mo f/up➡️ 46 recurrence (~90% in 24 mo)🇧🇷

Adjuvant chemotherapy (done in 46% patients)➡️ 3.9-fold ⬆️disease-free survival

Other risk factors - affected lymph nodes, surgical tumor size

No effect - radiotherapy

#FrontOncol 2025
www.frontiersin.org/journals/onc...

Frontiers | Identification of potential biomarkers for breast cancer based on salivary metabolomics IntroductionBreast cancer (BC) remains the most prevalent malignant tumor in women worldwide and a leading cause of cancer-related mortality. Early screening...

Identification of potential biomarkers for breast cancer based on salivary metabolomics #FrontOncol #MassSpec www.frontiersin.org/journals/onc...

Frontiers | Machine learning assisted breathomic approach for early-stage thoracic cancer detection ObjectiveThis study explores the feasibility of using breathomic biomarkers analyzed by machine learning as a non-invasive diagnostic tool to differentiate b...

Machine learning assisted breathomic approach for early-stage thoracic cancer detection #FrontOncol #MassSpec www.frontiersin.org/journals/onc...

Frontiers | Characteristic metabolite profile of 10 colorectal cancer-related bacteria BackgroundTumor metabolomics of colorectal cancer (CRC) is significantly different from normal tissues, due to nutrient deprivation, metabolite accumulation,...

Characteristic metabolite profile of 10 colorectal cancer-related bacteria #FrontOncol #MassSpec www.frontiersin.org/journals/onc...

#MetaplasticBreastCancer
Non-surgical patient

N=92 + 30

In both cohorts, chemotherapy is associated with improved Overall survival

"Radiotherapy can improve quality of life by alleviating debilitating symptoms" in advanced MpBC

#FrontOncol 2025
www.frontiersin.org/journals/onc...

Frontiers | Nontargeted metabolomics uncovering metabolite signatures in glioblastoma: a preliminary study on candidate biomarker discovery for IDH subtyping and survival prediction BackgroundCurrently, there are no established tumor-derived metabolic biomarkers in clinical practice that can simultaneously differentiate among nontumorous...

Nontargeted metabolomics uncovering metabolite signatures in glioblastoma: a preliminary study on candidate biomarker discovery for IDH subtyping and survival prediction #FrontOncol #MassSpec www.frontiersin.org/journals/onc...

Frontiers | Metabolomics for early-stage lung adenocarcinoma: diagnostic biomarker screening

Metabolomics for early-stage lung adenocarcinoma: diagnostic biomarker screening #FrontOncol #MassSpec www.frontiersin.org/journals/onc...

Re-analysis of 4 microarray transcriptomes
3x Endometriosis 1x Endometrial Cancer

Why these 4 (>10-yr old), instead of scRNAseq & spatial transcriptomics for endometrial lesions

FGF9 identified as a hub gene⬇️in abnormal endometrial tissues

#FrontOncol 2024
www.frontiersin.org/journals/onc...