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Overrepresentation analysis for the royalblue module, significantly associated to samples with unique TE insertions shows enrichment for cell cycle gene sets

Overrepresentation analysis for the royalblue module, significantly associated to samples with unique TE insertions shows enrichment for cell cycle gene sets

Finally, we used mRNA-seq from #GEUVADIS LCLs to conduct #WGCNA and identify gene modules associated with unique #TE copies. Strikingly, samples with unique insertions showed increased cell cycle gene expression 🧬, consistent with the known propensity for #TEs to expand in dividing cells. 7/8

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