New research in #RESInsectMolecBio
Carbohydrate #biosynthesis pathway is associated with lineage-specific #diapause termination in the #silkworm, #Bombyx mori
doi.org/10.1111/imb.70015
#Ontology #DEGs #WGCNA #Sericulture
@sassanasgari.bsky.social @gulianusslab.bsky.social @wileyeco.bsky.social
By generating species-wise gene coexpression #networks ( #WGCNA) and gene regulatory networks, we compared the QDR-driving networks of S. pennellii and S. lycopersicoides. We observed some overlap between both networks, but also a considerable number of species-specific nodes.
Check also #InSituCor which adapts #WGCNA by using spatial information
Paper: www.science.org/doi/10.1126/...
Code: github.com/Nanostring-B...
#SpatialBiology
We integrated several physiological and transcriptome data into a web tool specifically designed to advance seed maturation research, serving as a unique resource for the scientific community. #seedresearch #wgcna #transcriptome
bioinformatics.nl/SeedMatExplo...
Overrepresentation analysis for the royalblue module, significantly associated to samples with unique TE insertions shows enrichment for cell cycle gene sets
Finally, we used mRNA-seq from #GEUVADIS LCLs to conduct #WGCNA and identify gene modules associated with unique #TE copies. Strikingly, samples with unique insertions showed increased cell cycle gene expression 🧬, consistent with the known propensity for #TEs to expand in dividing cells. 7/8
Listening to Genevieve Konopka talking about the molecular networks underlying human cognition. #mbiosys17 #WGCNA