To test their findings, the researchers isolated a protein associated with aging in the aortas of mice, and injected it into young mice to observe the results. Animals treated with the protein had reduced physical performance, decreased grip strength, lower endurance, and lower balance and coordination compared to non-treated mice. They also had prominent markers of vascular aging.

The study identified a senoprotein, Gas6. Gas6 is a vitamin K dependent protein. The original study is paywalled, so I can't get details on whether Gas6 was carboxylated or not. Link to journal article: doi.org/10.1016/j.ce...
#Aging #Gas6 #VitaminK #CardioVascularDisease

Dramatic Decrease of Vitamin K2 Subtype Menaquinone-7 in COVID-19 Patients (1) Background: Vitamin K (VK) is a fat-soluble compound with a common chemical structure, a 2-methyl-1,4-naphthoquinone ring, and a variable aliphatic side-chain. VK is involved in the synthesis of b...

pmc.ncbi.nlm.nih.gov/articles/PMC...

"Vitamin K may also suppress #IL6 production, both indirectly through its activation of the immune inhibitory proteins growth-arrest-specific gene 6 ( #Gas6) and protein S,"