Phase Behavior of TDP-43 and hnRNP H1: From Soluble and Aggregated States to Liquid-Like Droplets Cytotoxic inclusions of TAR DNA-binding protein 43 (TDP-43) have been identified in various neurodegenerative diseases. Mediated by its low-complexity C-terminal domain (CTD), TDP-43 can undergo liqui...

Updated pre-print published on TDP-43 phase transition controlled by effective method, #LLPS, #LCD, #hnRNP
www.biorxiv.org/content/10.1...

An expansion of the phenotype in individuals with SYNCRIP-Related Neurodevelopmental Disorder. Disruption of genes within the HNRNP gene family has been observed in neurodevelopmental and neurodegenerative diseases. The HNRNP-Related Neurodevelo…

New #HNRNP paper out! We’ve learned a lot about SYNCRIP/HNRNPQ-Related Neurodevelopmental Disorder in the last few years! www.sciencedirect.com/science/arti...