Haplomics: A Snakemake pipeline for haplotype-based association analysis in multi-omics studies Summary Genome-wide association studies (GWAS) generated thousands of loci associated with complex traits and diseases. However, to characterize of the pleiotropic, molecular and population genetic bo...

To finish with #haplomics a #snakemake pipeline to run haplotype analysis at any locus , also available on #github
www.medrxiv.org/content/10.1...

Clinical and Metabolic Signatures of FAM47E–SHROOM3 Haplotypes in a General Population Sample Genome-wide association studies (GWAS) identified a locus on chromosome 4q21.1, spanning the Family With Sequence Similarity 47 Member E (FAM47E), Starch Binding Domain 1 (STBD1), Coiled-Coil Domain C...

Initial tests that were instrumental to build #Haplomics were applied to the #SHROOM3 locus for kidney function, revealing more complex population profiles

www.kireports.org/article/S246...

Haplomics: A Snakemake pipeline for haplotype-based association analysis in multi-omics studies Summary Genome-wide association studies (GWAS) generated thousands of loci associated with complex traits and diseases. However, to characterize of the pleiotropic, molecular and population genetic bo...

As a post-GWAS analysis, ever thought about automatic haplotype testing @ each locus + test vs any number of traits?
👏 Amazing @dariushghasemi.bsky.social just released #Haplomics, a #Snakemake pipeline walking u all the way down to summary stats+clustering
www.medrxiv.org/content/10.1...
#statgen