Very proud of this collaboration with Elly Tanaka and Elad Bassat. Jorge Peña @jpenap.bsky.social from our lab skillfully conducted our contributions. @regen-hearts.bsky.social #HeartRegeneration
1/ Can #Axolotls teach us new things about #HeartRegeneration?
A great collaboration between Elly Tanaka and Miguel Torres labs.
We’re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that?
doi.org/10.64898/202...
More new work from the lab! @idrm.ox.ac.uk @oxforddpag.bsky.social
Do all zebrafish regenerate their hearts equally? Also featuring the Mexican cavefish☺️
Thanks to all co-authors and especially the incredibly talented DPhil student Kostas Lekkos who drove the project. #zebrafish #heartregeneration
Schematic overview of cardiomyocyte regulators orchestrating the dedifferentiation, proliferation, and redifferentiation process
Cell Regen Review | Rewiring cardiomyocyte identity & metabolism for heart regeneration! 🫀 Strategies for improving cardiac function in animal models. #HeartRegeneration #StemCells
🔗 More at: doi.org/10.1186/s136...
New work from the lab! Cellular processes key for successful heart regeneration occur at specific times over 24 hours and disturbing these day-night rhythms affects cardiomyocyte metabolism, cell cycle and regeneration.
#zebrafish #cavefish #heartregeneration
www.linkedin.com/posts/gennar...
Please vote for my #ARTxSCIENCE2025 submission! Voting takes 10 secs
renew.science/artxscience/...
My image shows stem-cell derived heart cells treated with a drug that makes cardiomyocytes (pink) proliferate—without activating fibroblasts #HeartRegeneration #Microscopy #StemCells
#PaulKornerSeminar speaker Gabrielle Smith: 'Studying the #epigenome of regenerating cardiomyocytes: how do iPSC-derived cardiomyocytes invoked to re-enter cell cycle compare to animal #HeartRegeneration models?'
@em6wong.bsky.social
#PaulKornerSeminar speaker Gabrielle Smith: 'In Regulatory Systems lab, I am studying chromatin architecture and the #epigenome of cardiomyocytes across multiple animals to understand how genome regulation and evolution have shaped #HeartRegeneration across vertebrates.'
@em6wong.bsky.social
This review outlines the emerging endogenous key modulators of cardiomyocyte proliferation, elucidates the underlying internal mechanisms of #heartregeneration, and highlights the role of key molecules in the multimodal regulation of pre-existing #CardiomyocyteProliferation.
#CardiacImmunology #HeartRegeneration #DevelopmentalBiology #CardiacNiches #Genomics #InVitroSystems #Technology #Therapeutics #ScienceSky 🧪
A new study in experimental animals reveals a critical difference in how #macrophages help #repair the #heart in #newborns versus #adults after a #HeartAttack, highlighting a fundamental difference in how the #ImmuneSystem drives #healing.
#HeartRegeneration #CardiacRegeneration
Our final #PaulKornerSeminar speaker for today, Gabrielle Smith, will be presenting: ‘Cardiomyocyte chromatin conformation in regenerative and non-regenerative responses to injury’
#HeartRegeneration #CardioTwitter @em6wong
September's Star Scientist Dr Amy Nicks is on a mission to find the gene that could be the key to unlocking #HeartRegeneration. She's studying #cardiomyocytes that not only self-repair but are also 'beautiful' structures:#WomeninSTEM
victorchang.edu.au/blog/amy-nicks
#PaulKornerSeminar speaker Dr Amy Nicks: “We developed a new method to capture heart cells in their native state that shows how a baby/neonatal heart cell divides into two cells.” #HeartRegeneration #CellDivision #ConfocalMicroscopy #science #CardiacResearch #HeartResearch
#PaulKornerSeminar speaker Dr Amy Nicks: “Heart cells (or cardiomyocytes) are so beautifully engineered and grow dramatically with age as heart mass increases.” #HeartRegeneration #CellDivision #ConfocalMicroscopy #science #CardiacResearch #HeartResearch