These cells in the body remember fat. Here’s what that means for weight loss Obesity leaves a lasting imprint on fat and immune cells in ways that might make weight regain harder to avoid

"Cells that store fat, or adipocytes, and immune cells, such as macrophages, that live in fat tissue can remember weight long after it’s lost. And scientists suggest obesity causes lasting changes to those cells"

#Obeisty #Health #Cells #Metabolism #Epigenome

Photorespiration is linked to DNA methylation by formate as a one-carbon source - Nature Plants This study reveals that Arabidopsis reassimilates formate produced during photorespiration via the cytosolic folate cycle to fuel DNA methylation, forming a metabolic–epigenetic bridge that links elev...

#Photorespiration fuels C1 metabolism to support DNA methylation in Arabidopsis, linking photosynthetic C flux to #epigenome stability & showing how rising CO₂ can reshape the plant #methylome.

by #ValentinHankofer &
@martingroth.bsky.social

With contributions by
@andreaghirardo.bsky.social

There's still time to register to attend the Brain (epi)genome EMBO Workshop, to be held at EMBL Heidelberg 21 - 24 Apr 2026!! 🧠
Register to attend in person or virtually here:
www.embl.org/about/info/c...
#brain #genome #epigenome
@events.embl.org

@embo.org

🎥 #AgingShort:
Abstract #video about the #research paper, “Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring."

🔗 www.aging-us.com/article/2063...

#aging #TrendingWithImpact #autism #sperm #epigenome #oa

Ready to enhance your research? Don't miss this insightful webinar from @epicypher.bsky.social !

#genomics #genome #epigenome #DNA #molecularbiology

I finally got around to putting together a quick overview of what my book is all about.

youtu.be/xPt1xy4_i-o?...

#epigenetics #epigeneticsbook #epigenome

Close up of lilacs. The Canadian Science Publishing logo sits in the top left corner and the Canadian Science Publishing blaze emblem sits in the bottom right.

Genome welcomes unlimited fee-free open access submissions from @crkn-rcdr.bsky.social authors and provides unlimited Read Access to all @cdnsciencepub.com research. Publish with us 🍁▶️ buff.ly/oUyzd2x

🧬🔄 #genomics #chromatin #nucleosome #regulatorynetwork #generegulation #epigenome

Confederation Bridge in PEI, Canada. The Canadian Science Publishing logo sits in the top left corner and the Canadian Science Publishing blaze emblem sits in the bottom right.

Publish your next breakthrough in Genome with no fees. Corresponding authors with @crkn-rcdr.bsky.social can submit unlimited OA manuscripts and benefit from unlimited read access. Discover how 🍁▶️ buff.ly/oUyzd2x

🧬🔄 #genomics #chromatin #nucleosome #regulatorynetwork #generegulation #epigenome

Lysosomes signal through the epigenome to regulate longevity across generations The epigenome is sensitive to metabolic inputs and is crucial for aging. Lysosomes act as a signaling hub to sense metabolic cues and regulate longevity. We found that lysosomal metabolic pathways sig...

In #celegans, #lysosomes signal through the #epigenome to boost #transgenerational longevity.

Lipid & AMPK signals, or reduced mTOR, reprogram histone H3.3, which is transported from the #intestine to the #germline, extending #lifespan across generations.

www.science.org/doi/10.1126/...

Tsukuba Conference 2025 RIKEN BRC CONCURRENT SESSION | RIKEN BioResource Research Center RIKEN BioResource Research Center will participate in Tsukuba Conference 2025 and hold a concurrent session on Oct 1, 2025. Please register in advance (registration is until noon on Sep 30 (Tue.))…

🧬BRC Session @ Tsukuba Conference 2025
Oct 1 (Wed), 13:30–16:30｜Tsukuba International Congress Center
"Sustainable Future Shaped by Diverse Epigenome and Genome Research"
web.brc.riken.jp/en/archives/...
#TsukubaConference2025 #RIKEN #Epigenome #Sustainability

Rejuvenate Cells, Slow Aging - Jacob Kimmel and Dwarkesh Patel

#epigenome #transcriptionfactors

Close up of beaver stepping into water. The Canadian Science Publishing logo sits in the top left corner and the Canadian Science Publishing blaze emblem sits in the bottom right.

Genome welcomes unlimited fee-free open access submissions from @crkn-rcdr.bsky.social authors and provides unlimited Read Access to all research. Publish with us 🍁▶️ buff.ly/oUyzd2x

🧬🔄 #genomics #transcriptionfactor #chromatin #nucleosome #regulatorynetwork #generegulation #epigenome

Postdoctoral Research Fellowship in Chromatin Biology and Cancer Epigenetics (283381) | University of Oslo Job title: Postdoctoral Research Fellowship in Chromatin Biology and Cancer Epigenetics (283381), Employer: University of Oslo, Deadline: Wednesday, August 20, 2025

Two days left to apply for a 3-year postdoc in #Chromatin #Cancer #Epigenetics at University of Oslo, Norway, co-supervised by @amathelier.bsky.social You will be part of @cancelluio.bosky.social. We focus on #Sarcoma #Epigenome #CRISPR and Drug screen studies. Find out more here: shorturl.at/DtLHM

Postdoctoral Research Fellowship in Chromatin Biology and Cancer Epigenetics (283381) | University of Oslo Job title: Postdoctoral Research Fellowship in Chromatin Biology and Cancer Epigenetics (283381), Employer: University of Oslo, Deadline: Wednesday, August 20, 2025

We are hiring! A 3-year postdoc in #Chromatin #Cancer #Epigenetics at University of Oslo, Norway and co-supervised by @amathelier.bsky.social You will be part of @cancelluio.bosky.social. We focus on #Sarcoma #Epigenome #CRISPR and Drug screen studies. Find out more and apply here: shorturl.at/DtLHM

Close up of lilacs. The Canadian Science Publishing logo sits in the top left corner and the Canadian Science Publishing blaze emblem sits in the bottom right.

Genome welcomes unlimited fee-free open access submissions from @crkn-rcdr.bsky.social authors and provides unlimited Read Access to all @cdnsciencepub.com research. Publish with us 🍁▶️ buff.ly/oUyzd2x

🧬🔄 #genomics #chromatin #nucleosome #regulatorynetwork #generegulation #epigenome

Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains - BMC Biology Background Pig brains serve as a valuable biomedical model for studying brain-related diseases due to their significant structural similarities to the human brain. Furthermore, the long-term domestica...

Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains

#singlecell #epigenome #transcriptome #RNAseq #ATACseq #cortex #cerebellum #oligodendroglia 🧪

bmcbiol.biomedcentral.com/articles/10....

33/ We'd love to get feedback from the community #neuroinflammation #multiplesclerosis #Alzheimer #microglia #iPSC #CRISPR #Perturbseq #GWAS #epigenome #neurodegeneration

#PaulKornerSeminar speaker Gabrielle Smith: 'Studying the #epigenome of regenerating cardiomyocytes: how do iPSC-derived cardiomyocytes invoked to re-enter cell cycle compare to animal #HeartRegeneration models?'
@em6wong.bsky.social‬

#PaulKornerSeminar speaker Gabrielle Smith: 'In Regulatory Systems lab, I am studying chromatin architecture and the #epigenome of cardiomyocytes across multiple animals to understand how genome regulation and evolution have shaped #HeartRegeneration across vertebrates.'
‪@em6wong.bsky.social‬

Confederation Bridge in PEI, Canada. The Canadian Science Publishing logo sits in the top left corner and the Canadian Science Publishing blaze emblem sits in the bottom right.

Publish your next breakthrough in Genome with no fees. Corresponding authors with @crkn-rcdr.bsky.social can submit unlimited OA manuscripts and benefit from unlimited read access. Discover how 🍁▶️ buff.ly/oUyzd2x

🧬🔄 #genomics #chromatin #nucleosome #regulatorynetwork #generegulation #epigenome

How can cutting-edge tech help decode the complex #epigenome to reveal disease mechanisms, biomarkers & new therapies? Join us for the Unlocking the Epigenome: Precision Tools for Complex Diseases webinar series to find out. #epigenetics
Register now: hubs.la/Q03pFXJk0

Background image is a goose spreading its wings. The Canadian Science Publishing logo sits in the top left corner and the Canadian Science Publishing blaze emblem sits in the bottom right.

New! Unlimited open access publishing in Genome—no fees for corresponding authors at @crkn-rcdr.bsky.social affiliated universities. Plus gain unlimited Read Access to every article!

Publish with us 🍁▶️ buff.ly/oUyzd2x

#AcademicSky 🧪🧬🔄 #chromatin #nucleosome #generegulation #epigenome #genomics

At @mcgill-hg.bsky.social, @langlaislab.bsky.social is studying how the #epigenome regulates which #genes are expressed, and what happens when this does not go to plan.
futurumcareers.com/unveiling-th...
#scicomm #edusky

In our latest collection of #open_education_resources we explore #genomics with @langlaislab.bsky.social at @mcgill-hg.bsky.social. Discover how the #epigenome impacts the #immunesystem.
futurumcareers.com/unveiling-th...
#scicomm #edusky

Multi-omics integration reveals potential stage-specific druggable targets in T-cell acute lymphoblastic leukemia

An integrated #multiomics approach identified 29 pathological genes in T-ALL, of which four are known druggable targets with dysregulated & stage-specific expression in malignant T cells that may serve as stage-specific targets in the treatment of T-ALL. #Transcriptome #epigenome

buff.ly/00ddQDh

Still new on 🦋 but thrilled to share that I will be chairing with @lopeslab.bsky.social the next series of virtual seminars from @genomeiinetwork.bsky.social! Join us for the most exciting, thought-provoking, latest findings in the field! 👇Please repost
#genomeinstability #DDR #Senescence #epigenome

Welcome! You are invited to join a webinar: CEEHRC March 21, 2025 - Arrowsmith & Horvath. After registering, you will receive a confirmation email about joining the webinar. The Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC) Network is a network run by epigenetic researchers from across Canada, funded by the Canadian Institutes of Health Researc...

Our next seminar is this Friday, March 21! This week, we welcome Drs. Cheryl Arrowsmith and Riley Horvath from University of Toronto 🇨🇦 where they will discuss pharmacological tools for manipulating the #epigenome.

FREE to register - us06web.zoom.us/webinar/regi...

Welcome! You are invited to join a webinar: CEEHRC March 21, 2025 - Arrowsmith & Horvath. After registering, you will receive a confirmation email about joining the webinar. The Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC) Network is a network run by epigenetic researchers from across Canada, funded by the Canadian Institutes of Health Researc...

Our next seminar is this Friday, March 21!

This week, we welcome Drs. Cheryl Arrowsmith and Riley Horvath from @uoft.bsky.social where they will discuss pharmacological tools for manipulating the #epigenome.

Register at: us06web.zoom.us/webinar/regi...

Frontiers | Childhood obesity from the genes to the epigenome The prevalence of obesity and its associated comorbidities has surged dramatically in recent decades. Especially concerning is the increased rate of childhoo...

REVIEW: Childhood #obesity from #genes to #epigenome @dream-diabetes.bsky.social www.frontiersin.org/journals/end...

Activating Complex Regions of the Genome to Treat Rare Diseases | Duke Pratt School of Engineering Researchers find a master epigenetic switch that activates silenced genes to compensate for their missing counterparts in a rare genetic disease called Prader-Willi syndrome

Researchers find a master #epigenetic switch that activates silenced genes to compensate for their missing counterparts in a rare genetic disease called #Prader-Willi syndrome
pratt.duke.edu/news/crispr-...
#epigenome #genomics #CRISPR