Oral 4′-fluorouridine rescues nonhuman primates from advanced Lassa fever - Nature Treatment with 4′-fluorouridine (also known as EIDD-2749) in an African green monkey (Chlorocebus aethiops) model of Lassa disease resulted in complete clearance of infectious virus in a high proportion of cases and prolonged survival to the pre-determined study end-point in all cases.

Emerging infectious diseases

New in Nature: the oral antiviral 4′-fluorouridine protected non-human primates from lethal Lassa fever when administered at an advanced stage of infection.

Read more: https://www.nature.com/articles/s41586-025-09906-y

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