A Drosophila wing imaginal disc expression nej/CBP-RNAi in the posterior compartment under control of en-GAL4. Loss of H3K27ac is visualized by IF (magenta) and the resulting cell cycle arrest is visualized by expression of the FUCCI reporter (green for G1 and yellow for G2).

#CellCycle progression is linkied to #HistoneModification dynamics, but how is this regulated in vivo? @classenlab.bsky.social &co show that levels of H3K27ac, H3K27me3 & H3K9me3 are tightly linked to cell cycle dynamics in the #Drosophila wing imaginal disc @plosbiology.org 🧪 plos.io/4bPkPbv