#ISV2017 Wiedermann: IgG same, IgM / IgA higher in obese - influence of raised IL6? Low persistent inflammation milieu in obese individuals.
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Hashtag
#ISV2017
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#ISV2017 Ursula Wiedermann: obesity epidemic is impacting immune responses - testing tick-borne encephalitis vaccine responses.
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#ISV2017 Fingermann: OMVs protect mice from lethal E coli challenge. Cattle trial: post-weaning calves, 50-100ug/dose - cheap!
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#ISV2017 Matias Fingermann: Outer membrane vesicles derived from E coli as vaccines in cattle: simple, validated manufacture process
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#ISV2017 Annie de Groot, Epivax: H7N9 HA from 2013 has Treg epitope suppressing antibody response: knocking in a Teff epitope instead helps!
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#ISV2017 Alharbi: ChAdOx MERS vaccine boosts previously infec camels well but >1 dose needed for naive and esp young camels. Human use poss?
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#ISV2017 Sultan Gulce-Iz on CCHFV: nice protein microarray screening results on human sera; interesting mucin-like domain and GP38 reactions
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#ISV2017 @PeterHotez gave a GREAT talk on NTDs in LMICs - and vaccine advocacy. Oh, and use of Twitter B-)
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#ISV2017 Lesedi Modipane #Tuks #UP: doing you proud, NHLS! Whole genome sequening of South African clinical BCG isolates
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#ISV2017 EpiVax Inc: has provided IVAX Toolkit: cloud-based tool for safer, better, faster vaccine design, esp for "string of beads" designs
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#ISV2017 US Army making a vaccine to heroin - that also interferes with "abused" opoid effects. What about when a former abuser needs them??
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#ISV2017 "My wife happens to be the manager of the BSL4 facility..." - good planning, that! Definitely facilitates collaboration B-)
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2/2 #ISV2017 ...forget that TMV and other rodlike/filamentous plant viruses encapsidate big RNAs really well AND target DCs.
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#ISV2017 Interesting talks on self-replicating RNA vectors and lipid nanoparticles: good combo with tunable targetting. But people 1/2
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#ISV2017 Louis Picker: can engineer CMV for unconventional T-cell responses, and can superinfect and express lifelong. Works for TB in NHPs?
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#ISV2017 Jansen: Fluoroquinolone resistant C difficile spread worldwide from two separate mutation events - but vaxx in dev look good??
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#ISV2017 Jansen: Looks like time from intro to development of AMR for any given abiotic is shrinking into present
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#ISV2017 Jansen 2/2: ...in developing countries and esp India and Pakistan
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#ISV2017 Kathrin Jansen Pfizer: neonate deaths due to sepsis caused by bacteria resistant to first-line antibiotics now a major problem 1/2
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#ISV2017 GREAT talk by Felix Rey of Inst Pasteur on flavivirus surface structure and relevance to vaccines and ADE.
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Damn, but there's a lot of hand-waving around HIV vaccine correlates of protection! #ISV2017 Lesson: there's no substitute for clin trial
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2/2 #ISV2017 Kaufman: ...- and is still world's biggest infectious disease killer
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Stefan Kaufmann #ISV2017 TB has historically killed more peoplle than malaria, plague, flu and HIV COMBINED 1/2
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Scientists from 36 countries together at #ISV2017!
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#ISV2017 Margartet Lie: vaccines are a victom of their own success - partly because risk:benefit ratios have changed
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So: #ISV2017 is the hashtag - and let the tweeting commence....
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