ROCK inhibitors #Fasudil #Belumosudil suppresses 🐭 #SubretinalFibrosis with laser-induced choroidal neovascularization

Cool #ImagingMassCytometry 25 antibodies with metal isotopes for single-cell ocular pathology🤠

#ResearchSquare 2025
www.researchsquare.com/article/rs-4...

Simultaneous expression of epithelial and immune cell markers in circulating tumor cells identified in patients with stage 4 breast cancer - Communications Medicine Higa et al. analyzed circulating cells expressing cancer and immune cell markers in breast cancer patients. Based on genomic and protein expression profiling, they show that the cells were unlike prev...

New from @usc.edu : Peter Kuhn & James Hicks use CyTOF + IMC to profile rare immune-like CTCs (CD45⁺/CK⁺) in metastatic breast cancer. A novel hybrid cell type with clinical potential.

www.nature.com/articles/s43...

#SpatialBio @standardbiology.bsky.social #ImagingMassCytometry

An excellent paper by Joel Eliason, Jared K. Burks, Suhendan Ekmekcioglu et al on characterizing the spatial immune architecture in melanoma using imaging mass cytometry #IMC.

www.frontiersin.org/journals/imm...

@standardbiology.bsky.social @visiopharm.bsky.social #SpatialBio #ImagingMassCytometry

An excellent paper by Daniel W Rosenberg et al using #IMC makes the cover of the issue of AACR Journals Cancer Prevention Research being handed out at #AACR25. Congratulations!

aacrjournals.org/cancerpreven...

#ImagingMassCytometry @standardbiology.bsky.social #SpatialBio

CD103+CD56+ ILCs are associated with an altered CD8+ T-cell profile within the tumour microenvironment Abstract. Immunotherapies have had unprecedented success in the treatment of multiple cancer types, albeit with variable response rates. Unravelling the complex network of immune cells within the tumo...

An exciting new paper from Pamela Ohashi, Hartland Jackson, et al, on CD103+CD56+ innate lymphoid cells in the tumor microenvironment.

aacrjournals.org/cancerimmuno...

#spatialbiology #TME #IMC #imagingmasscytometry @standardbiology.bsky.social #UHN_Research

SpiDe-Sr
Spatial proteomic images denoising & super-resolution
#SpatialProteomics

⏫peak signal-to-noise ratio & cell extraction accuracy in #ImagingMassCytometry

Also applicable to immunofluorescent images

vs SRCNN KernelGAN RCAN

#NatureComms 2024
www.nature.com/articles/s41...