This review describes aberrant #Sialylation as a critical driver of malignancy and #ImmuneSuppression, highlighting glycan-targeting strategies and sialyltransferase inhibitors as promising avenues for #PrecisionOncology.

#OpenAccess: doi.org/10.1016/j.ge...

This review describes aberrant #Sialylation as a critical driver of malignancy and #ImmuneSuppression, highlighting glycan-targeting strategies and sialyltransferase inhibitors as promising avenues for #PrecisionOncology.

#OpenAccess: doi.org/10.1016/j.ge...

TuHURA Biosciences CEO Dr. James Bianco explains the mechanism of action for the Delta Opioid Receptor which modifies the tumor microenvironment rather than targeting the tumor itself.
$HURA
#ImmunoOncology #CancerResearch #CancerImmunotherapy #ImmuneSuppression #MDSCs
youtu.be/8xSUa9LjsNk

Obesity-associated fibroblasts reshape the #TME across #cancers, identify the TS.FIBRO.OBESITY.SIG signature linked to #ECM remodeling, #ImmuneSuppression and #TherapyResistance, and highlight key genes that may guide prognosis and treatment.

#OpenAccess: doi.org/10.1016/j.ge...

Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer The researchers show that disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment.

Researchers reveal a mechanism that allows triple negative #BreastCancer (#TNBC) to become #resistant to #therapy.
#XiangZhangLab, L. Yu et al #ImmunityCP #fattyAcids #ImmuneSuppression #BreastCancerAwarenessMonth @bcmhouston.bsky.social blogs.bcm.edu/2025/04/22/f...

Fatty acids promote immune suppression and therapy resistance in triple-negative breast cancer – BioNews Central New findings reveal a mechanism that enables triple-negative breast cancer to develop therapy resistance. ...

New findings reveal a mechanism that enables #TripleNegativeBreastCancer to develop #TherapyResistance.
#BreastCancer #ImmuneSuppression