Dr. Jewett's review examines how MDSCs inhibit NK cell anti-tumor activity through peptidases, highlighting therapeutic potential of peptidase inhibitors to enhance immune responses.

Free until March 15: dl.begellhouse.com/journals/2ff...

#MDSCs #Immunotherapy

TuHURA Biosciences CEO Dr. James Bianco explains the mechanism of action for the Delta Opioid Receptor which modifies the tumor microenvironment rather than targeting the tumor itself.
$HURA
#ImmunoOncology #CancerResearch #CancerImmunotherapy #ImmuneSuppression #MDSCs
youtu.be/8xSUa9LjsNk

TuHURA CEO Dr James Bianco explains how the delta opioid receptor (DOR) works and the way in which it affects immune system response
$HURA
#MDSCs #ImmunoOncology #CancerResearch #CancerTreatment #Oncology
youtube.com/shorts/eE8x8...

Dr Bianco introduces TuHURA’s Immune Modulating ADCs which link a VISTA inhibitor to a delta opioid receptor inhibitor to target the tumor microenvironment rather than the tumor itself
$HURA
#TumorMicroenvironment #ImmunoOncology #MDSCs #MyeloidCells #VISTA #Oncology #ADC youtube.com/shorts/jfTnJ...

Delta-like ligand 4 mediated myeloid-derived suppressor cell metabolic reprogramming promotes neoadjuvant therapy resistance in titin-inactivated triple-negative breast cancer - Molecular Biomedicine Triple-negative breast cancer (TNBC) is characterized by complex genomic background and treatment resistance. We first defined “Titin (TTN) inactivation”, a state of TTN expression deficiency or mutat...

#Research
Delta-like ligand 4 mediated myeloid-derived suppressor cell metabolic reprogramming promotes neoadjuvant therapy resistance in titin-inactivated triple-negative breast cancer doi.org/10.1186/s435...

#TNBC #TTNinactivation #MDSCs #GlycolyticMetabolism #DLL4_MCT4

Cervical mucosal inflammation expands functional polymorphonuclear myeloid-derived suppressor cells The mucosal immune system plays a fundamental role in maintaining microbial balance. Microbial imbalance in the female genital tract increases the ris…

What is the role of #MDSCs in the female genital tract during inflammation?

Read all about it in our new publication in @mucosalimmunol.bsky.social

www.sciencedirect.com/science/arti...

Thanks to our team @vhir.bsky.social led by @txellgenesca.bsky.social

#Womenshealth #MucosalImmunology #STI

TuHURA Biosciences Presents Groundbreaking Research on Delta Opioid Receptor and Cancer Immunotherapy TuHURA Biosciences announces groundbreaking findings on Delta Opioid Receptor's role in reprogramming immune cells, enhancing cancer treatment effectiveness.

TuHURA Biosciences Presents Groundbreaking Research on Delta Opioid Receptor and Cancer Immunotherapy #USA #Tampa #TuHURA_Biosciences #Delta_Opioid_Receptor #MDSCs

Congrats @el_deusu @HortovaMarcela @MartinHelan and team for @CSAC_CZ prize for 2nd best paper in clinical and applied cytometry in 2021. @FNUSA_ICRC #CTM @UHKT_cz #sepsis #MDSCs #FlowCytometry #metaclustering