Inflammation-Related Factors S100A9 and TLR2 in Cardiomyocyte Hypertrophy

A pathogenic S100A9–TLR2 feedback loop amplifies #hypertrophic and #InflammatorySignaling in mechanically stressed #cardiomyocytes, linking immune dysregulation to maladaptive #CardiacRemodeling and highlighting a therapeutic target in #HeartFailure.

Read: doi.org/10.1007/s115...

This review explores the role of #YTHDF2 in #ImmuneRegulation and #InflammatorySignaling, emphasizing its contribution to #disease #pathogenesis, the development of selective #therapeutic agents, and the challenges of #ClinicalTranslation. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

ISU Researchers Find Key Factor Linking Longer Maturation to Longer Life | Newswise An Iowa State University research team identified how developmental delays lead to longer lifespans in fruit flies, a potential model for exploring human longevity.

ISU Researchers Find Key Factor Linking Longer Maturation to Longer Life
www.newswise.com/articles/isu...
#longevity #LongerLifespan #Fruitflies #inflammatorysignaling #developmentaldelay #aging