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#IntJSurgPathol
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#MetaplasticBreastCancer
#CaseReport

MpBC with melanocytic components (melanA+S100+HMB45+Sox10+GATA3-)

Non-tolerated immunotherapy (ipilimumab nivolumab) ⏫TIL in melanocytic, not carcinomatous compartment

Mutation
TP53 PIK3CD TSC2 PTCH1

#IntJSurgPathol 2026
journals.sagepub.com/doi/10.1177/...

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