Researchers highlight how #PostTranscriptional regulation shapes #IntervertebralDisc homeostasis, identify aberrant RNA regulation as a driver of #discdegeneration, and present mechanistic insights to guide therapeutic repair.

#OpenAccess: doi.org/10.1016/j.ge...

Do we know more about the mechanobiology of the intervertebral disc in space than on Earth? This work provides a perspective on the loading protocols used in whole-organ interverterbal disc culture studies using bioreactors. We put this in the context of in vivo spinal loading, and we put f...

Excited to share our latest paper! We dive into what bioreactor IVD loading means for real-life conditions and how we can refine models to make findings clinically relevant.

Check it out here: onlinelibrary.wiley.com/doi/10.1002/...

#Spine #IntervertebralDisc #Bioreactor #Research