A framework for prospective, adaptive meta-analysis (FAME) of aggregate data from randomised trials Jayne Tierney and coauthors discuss FAME, an approach for adaptive meta-analysis of data from randomised trials.

#DADSPORT shows how collaboration can push aggregate data towards #IPD quality, but much quicker. Our #MetaAnalysis framework #JustFAMEIt has shown similar advantages in other projects, particularly if review can be designed & planned before trial results are known.
doi.org/10.1371/jour...