KAT6B Overexpression in Mice Causes Aggression, Anxiety, and Epilepsy - Redenlab A recent study published in iScience explores the effects of KAT6B overexpression in mice, shedding light on the behavioral implications of this gene. KAT6B gene variants in humans have been linked to...

New research in iScience shows KAT6B overexpression in mice causes aggression, anxiety, and epilepsy. KAT6B variants in humans are linked to cognitive disorders like SBBYSS and GTPTS, causing developmental delays.

redenlab.com/kat6b-overex...

#KAT6B #Neuroscience #Research #RareDiseases

Repressed but ready to go: How bivalency holds developmental genes in a poised state for expression As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site of modifications, chemical additions referred to as epigenetic marks, that ...

Repressed but ready to go: How #bivalency holds developmental #genes in a poised state for #expression.

#histones #H3K27me3 #H3K4me3 #Nucleosome #KAT6B

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