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#LifeEngineering
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Nediljko (Ned) Budisa
Nediljko (Ned) Budisa
@nedbudisa.bsky.social
6 months ago
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We highlight an alternative: breaking triplet degeneracy - reshaping how codons are read, not just hijacked.

Not tinkering with recoding tricks but redesigning the code’s architecture.

DOI: doi.org/10.1002/cctc...

#GeneticCode #LifeEngineering #SyntheticBiology #Xenobiology

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Nediljko (Ned) Budisa
Nediljko (Ned) Budisa
@nedbudisa.bsky.social
6 months ago
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If more stop codons mean less protein, can we really call this expansion? Recoding looks fragile - more in-frame stops give exponentially less protein. We need efficiency for true translational research.

DOI: doi.org/10.1002/cctc...

#GeneticCode #LifeEngineering #SyntheticBiology #Xenobiology

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Nediljko (Ned) Budisa
Nediljko (Ned) Budisa
@nedbudisa.bsky.social
6 months ago
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Life’s “operating system” is a universal genetic code. For billions of years it seemed frozen. In ChemCatChem we explain why it looks this way - and how we might carefully expand it.

DOI: doi.org/10.1002/cctc...

#GeneticCode #LifeEngineering #SyntheticBiology #Xenobiology

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