Detection of functional clusters (FCs) specific to the phenylalanine (PAL) and p-coumaroyltyramine (THT) pathways. Top left: Network depicting the relationship between transcripts and mass signatures within the PAL FC. Bottom left: Network illustrating the interplay between transcripts and mass signatures within the THT FC. Top right: Heatmap illustrating the expression levels of all transcripts within the PAL and THT FCs. Upper middle right: Heatmap displaying the abundance of all mass signatures present in the PAL and THT FCs. Lower middle right: Correlation matrix highlighting the correlations among transcripts and mass signatures within the PAL FC. Bottom right: Correlation matrix displaying the relationships between transcripts and mass signatures within the THT FC, including Mutual rank and transformed edge weights.
Elucidating #plant #Biosynthetic pathways: @jjjvanderhooft.bsky.social @marnixmedema.bsky.social &co develop #MEANtools, an unsupervised computational workflow that integrates #MultiOmics data to predict #metabolic pathways by linking transcripts to metabolites @plosbiology.org 🧪 plos.io/4odL94g