Epilogue: More info about Blastocystis virulence, specifically, can be found here in this comprehensive paper:
pmc.ncbi.nlm.nih.gov/articles/PMC...
@parasitesrule.org #MPM2025 #MPMXXXVI #Parasitology
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More general info about the mysterious #parasite Blastocystis and its contested #virulence can be found here:
frontline.thehindu.com/the-nation/p...
(Note that "subtypes" are incredibly genetically diverse!)
@parasitesrule.org #MPM2025 #MPMXXXVI #Parasitology
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There's mixed consensus whether Blastocystis is virulent - it's one of those microbes sitting on the fence between mutualism and parasitism. In my own work, virulence seemed to correlate with #microbiome composition.
Thanks to Zedan et al., we're now closer to a better understanding.
#MPM2025
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More highlights from #MPMXXXVI!
Work by Roaa Zedan et al. developed a point-of-care diagnostic test for #Blastocystis, a fascinating #protist found across the world (including industrialized nations) in the human gut #microbiome, implicated in diseases such as #IBS.
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@parasitesrule.org #MPM2025
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Check out their publication on this exciting and fascinating #research:
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
@parasitesrule.org #MPM2025 #MPMXXXVI #Parasitology
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Why do we care? Because very little information is available for proteins found in #parasites, despite parasites causing a third of the total global burden of human #disease (!!!) #MPM2025 @parasitesrule.org
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More about this problem is explained nicely here: www.sciencedirect.com/science/arti...
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More highlights from #MPMXXXVI!
Work by Lindsay Clark et al. predicts protein function based on existing gene sequences of #parasites in @veupathdb.org, annotating otherwise uncharacterized proteins based on their structure & helping inform drug discovery efforts.
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@parasitesrule.org #MPM2025
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(Don't forget to check out my own work on the subject! uniofnomi.wordpress.com/lab-log/)
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@parasitesrule.org #MPM2025 #Parasitology #AMR
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Co-author Marcelo Beltrão Molento has done impressive work showing the benefits of plant-based therapies in standard, agroecological, and holistic #farming systems to combat drug resistant #parasite populations: dx.doi.org/10.5380/avs....
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@parasitesrule.org #MPM2025 #Parasitology #AMR
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More highlights from #MPMXXXVI!
Work by Ismael L. Orbegon et al. shows Verbena litoralis, a medicinal plant, has significant in vitro activity against parasitic worms infecting sheep, showing promise for addressing the growing threat of drug resistance.
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@parasitesrule.org #MPM2025 #Parasitology
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More highlights from #MPMXXXVI:
Work by Lum Abienwi Ambe et al. has begun to develop a non-invasive assay for detecting Onchocerca volvulus from urine samples, making it easier to treat #onchocerciasis - a devastating parasitic #disease causing blindness.
@parasitesrule.org #MPM2025 #Parasitology
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The final tally of the @veupathdb.org user comments campaign at #MPM2025: Most user comments were entered on AmoebaDB followed by PlasmoDB, and then ToxoDB. 🎉
🏆The real winners: All VEuPathDB users, who benefit from current and reliable gene information!
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The @veupathdb.org user comments campaign at #MPM2025 yielded 200 user comments from 66 attendees! Thanks, contributors 💐
For example: a comment on gene cgd5_3570 on CryptoDB pointed out that GGC proteins exhibit male-specific expression according to single-cell RNA seq. Good to know!
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Hey, #MPMXXXVI attendees! Just a reminder today is the last day to vote for your favourite talks and posters from this year's meeting. I've highlighted a few in my posts below!
@parasitesrule.org #MPM2025 #Parasitology
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Highlights from #MPMXXXVI:
#Ticks! (woot!) Work by Isaac A. Hinne et al. identified stage-specific gene expression profiles in developing #tick embryos (Ixodes scapularis).
Targeting embryonic development in ticks offers a unique point of #vector control.
@parasitesrule.org #MPM2025 #Parasitology
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Learn more about some of their work here: pmc.ncbi.nlm.nih.gov/articles/PMC...
(Although ginger extract is used in this paper^. If anyone can point me towards publications of their studies using thyme extract please do!)
@parasitesrule.org #MPM2025 #Parasitology #MPM2025 #botany
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How? By inhibiting the uptake of metabolically essential amino acids and disrupting the parasite's lifecycle.
You can learn more about some of their work here: pmc.ncbi.nlm.nih.gov/articles/PMC...
#Parasitology #MPMXXXVI #MPM2025
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Highlights from #MPMXXXVI:
Work by Melisa Sayé et al. explores repurposing benztropine - a Parkinson's disease drug - against infection by Trypanosome cruzi, a #parasite causing Chagas disease which affects >7 million people worldwide.
@parasitesrule.org #MPM2025 #Parasitology
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Here is just one implication for ease-of-use #AI tools that can assist #healthcare in considering #parasites as relevant pathogens: theconversation.com/toxoplasma-i...
#MPM2025 #MPMXXXVI #Parasitology
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The medical #diagnosis of #parasites, despite its importance, is often overlooked given the lack of time and experts to do so. #AI tools can expedite the process and make #parasitology more amenable to #healthcare providers and testing labs, potentially saving lives.
#MPM2025 #MPMXXXVI
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Highlights from #MPMXXXVI:
A review by Dr. Mohammad Taghi Ahady et al. reveals high accuracy (>97%) of #AI and #MachineLearning tools in identifying #parasites in microscopic images of #medical samples, both blood and stool.
@parasitesrule.org #MPM2025 #Parasitology
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A super useful tool for your #bioinformatics workflow to compile data across databases (among other cool features!)
(Poster still accessible to #mpm2025 attendees for the next 2 weeks!)
Spread the word, & help keep @veupathdb.org up & running! Our #analysis is only as strong as our #data.
#R
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The 36th Molecular #Parasitology Meeting was a smashing success! Thanks @parasitesrule.org for bringing together parasitologists from around the world, reminding us why we love this #niche field of absolutely fascinating and #essential research.
#MPMXXXVI #mpm2025
www.parasitesrule.com/mpm-xxxvi
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Missed a talk at #mpm2025? Recordings are accessible for two weeks!
With an action-packed conference buzzing with parasitologists over just 5 days, the opportunity to re-watch our favourite presentations (or the ones where we may-or-may-not-have spaced out a little) is much appreciated!
#MPMXXXVI
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Honoured & grateful to have received an MPM Travel Grant and have the opportunity to present my PhD research at my first MPM 🇺🇸
Amazing science, inspiring discussions & a fantastic community of parasitologists – what a milestone in my journey. @parasitesrule.org
#MPM2025 #Parasitology
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Did you submit an abstract to #mpm2025? Notifications went out this week. Check you spam folders if you don't see an email in your inbox. @rmc9z.bsky.social @mjgubbels.bsky.social @omarharb.org
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The EU #EMFA regulation comes into force today: maximum pressure on the 11 states that do not guarantee the independence of public media (in dark red and bright red on the CMPF map).
#PressFreedom #MediaPluralism #PMS #EU #MPM2025
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🗞️Né rosso né verde, ma neppure giallo. Arancione.
È in questa fascia di colore che @eui-media-freedom.bsky.social colloca l’Italia nel suo #MPM2025, il Report con cui analizza lo status dei media in Europa 🇪🇺.
✍🏻 Ne parlo nella mia newsletter: elaniazito.substack.com/p/come-stann...
#Journalism
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#MPM2025 report is out. Best working conditions for journalists in #Denmark (10% risk) #Estonia (15%) and #Luxembourg (15%). Worst ones in #Greece (74%) #Turkey (71%) and #Serbia (68%).
cmpf.eui.eu/mpm-interact...
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#PluralismeDesMédias: le rapport européen #MPM2025 est sorti ce vendredi. Sur les 32 pays analysés par les chercheurs du CMPF, la Belgique et la Lituanie sont les deux pays qui affichent le plus haut degré de risque (respectivement 95% et 96%) en termes de concentration des opérateurs d'information!
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