Three-dimensional confocal image of a swine trophoblast organoid immunostained for ZO-1 (green) and actin (purple), with nuclei counterstained using DAPI (grey). ZO-1 highlights tight junctions at the apical borders in the center of the organoids, while actin outlines cellular architecture, revealing organized epithelial polarity within the organoid structure. Image credit: Cole McCutcheon, Duke University.
In vitro model of porcine placental development: @crm110.bsky.social &co develop a swine trophoblast #organoid model that mimics in vivo #trophoblast diversity & gene expression, providing a platform for studying #placental biology & #MaternalFetalInteractions @plosbiology.org 🧪 plos.io/47jf3yd