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๐Ÿ‘‡๐Ÿฝ Trial finding that led to approval:

Menin inhibitor revumenib showed promising efficacy in R/R NPM1-mutated AML โ€” CR + CRh = 23%, ORR โ‰ˆ 47%, median DOR ~ 4.7 mo, manageable QTc prolongation.
๐Ÿ“ˆ Led to FDA approval (2025) for R/R NPM1m AML.
#AML #Revumenib #MeninInhibitor doi.org/10.1182/blood.โ€ฆ

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