๐๐ฝ Trial finding that led to approval:
Menin inhibitor revumenib showed promising efficacy in R/R NPM1-mutated AML โ CR + CRh = 23%, ORR โ 47%, median DOR ~ 4.7 mo, manageable QTc prolongation.
๐ Led to FDA approval (2025) for R/R NPM1m AML.
#AML #Revumenib #MeninInhibitor doi.org/10.1182/blood.โฆ
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