#Mic60

Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast In eukaryotes, cellular respiration takes place in the cristae of mitochondria. The mitochondrial inner membrane protein Mic60, a core component of the mitochondrial contact site and cristae organizi...

Out in print! Using ancestral sequence reconstruction 🦖, in vivo characterization, and 🔬 analysis, we identified key residues in the mitochondrial protein #Mic60 that affect #respiration in #yeast.

Since the preprint, we added some cool findings. 🧵⬇️

onlinelibrary.wiley.com/doi/10.1002/...