A week with Judita Koreiviene, Jurate Karosiene and their Algology (Phycology) lab at the Natural Research Center in #Vilnius. We had fun setting up the HPLC method for #microcystins and organizing an HPLC seminar. A new collaboration has started and exciting results are coming soon....

Biotransformation Dynamics and Products of Cyanobacterial Secondary Metabolites in Surface Waters Cyanobacteria produce toxic and bioactive secondary metabolites, posing risks to ecosystems and human health, yet their transformation pathways in surface waters remain unclear. We assessed biotransfo...

Excited to share work by @xuejianwang.bsky.social where we provide biotransformation kinetics of cyanopeptides beyond #microcystins, influence of initial #toxins & bacteria, #transformation products & pathways!#cyanobacteria research done at @eawag.bsky.social pubs.acs.org/doi/10.1021/...

Differential impact of #microcystins MC-LR and [D-Leu1]MC-LR in different areas of the rat brain after chronic exposure:

Oxidative stress and antioxidant responses

www.sciencedirect.com/science/arti... #OpenAccess #cyanobacteria #MicroSky

#Microcystins as leads for drugs development ? Yes, and Timo Niedermeyer gave an excellent invited talk on this topic at #ICTC13. @timoniedermeyer.bsky.social @niedermeyer-lab.bsky.social

There is no magic formula which toxins are expected with #cyanobacteria but the #microcystins and #anabaenopeptins we identified as indicators for different species in Lake Greifensee in a 5-year study seem to apply to many lakes in Switzerland.

#Microcystins can be modified with click chemistry to turn into potential anticancer drugs. By the @timoniedermeyer.bsky.social lab.
@niedermeyer-lab.bsky.social
doi.org/10.1021/acs....