In senescent #MesenchymalStemCell

Nanog-induced Proline Biosynthesis via⏫key enzymes PYCR1/2 (not P5CS) ➡️
👉⏫Mitochondria functions via⏫AMPK-Parkin- #Mitopahgy
👉Revert #Senescence
👉⏫TGFβ1-induced #SmoothMuscleCell differentiation

@cp-cellreports.bsky.social 2024
www.cell.com/cell-reports...