Today’s first question highlights a key distinguishing feature of TEMPI syndrome in clinical practice.
#JAK2NegativeErythrocytosis #NonPVErythrocytosis #Erythrocytosis #Hematology #MyeloproliferativeDisorders #SecondaryErythrocytosis #EPO #Hypoxia #GermlineMutations #ClinicalHematology
Facts about JAK2 unmutated erythrocytosis:
Post-renal transplant erythrocytosis declines with ACEi/ARBs; management is monitoring and CV risk control, not routine phlebotomy or JAK2 inhibitors.
#JAK2NegativeErythrocytosis #Erythrocytosis #Hematology #MyeloproliferativeDisorders
Facts about JAK2 unmutated erythrocytosis:
In Chuvash polycythemia and high oxygen affinity hemoglobin, thrombosis risk is linked to age and cardiovascular factors—not hematocrit—and phlebotomy or hydroxyurea are generally not beneficial.
#Erythrocytosis #Hematology #MyeloproliferativeDisorders
Today’s question!
Check out the answer on the next slide along with its explanation.
#Hematology #Medicine #Erythrocytosis #MyeloproliferativeDisorders @ash.edu.hematology.org @bsochaem.bsky.social @rarediseasectn.bsky.social @rarediseasesint.bsky.social @ash.hematology.org @vjhemonc.bsky.social
Today’s question!
Check out the answer on the next slide along with its explanation.
@ash.edu.hematology.org @rarediseasectn.bsky.social @rarediseasesint.bsky.social @bsochaem.bsky.social @vjhemonc.bsky.social #Erythrocytosis #Hematology #MyeloproliferativeDisorders #SecondaryErythrocytosis #EPO
Today’s question!
Check out the answer on the next slide along with its explanation.
#NonPVErythrocytosis #Erythrocytosis #Hematology #MyeloproliferativeDisorders #SecondaryErythrocytosis @vjhemonc.bsky.social @bsochaem.bsky.social @ash.edu.hematology.org
Facts about JAK2 Unmutated Erythrocytosis:
In hereditary erythrocytosis, HOAV can explain normal/high Epo. Modern labs use HPLC and mass spectrometry instead of P50. PIEZO1 mutations expand the genetic spectrum.
#Erythrocytosis #Hematology #MyeloproliferativeDisorders
Today’s question!
Check out the answer on the next slide along with its explanation.
#Erythrocytosis #Hematology #MyeloproliferativeDisorders #Hematology #Hypoxia @bsochaem.bsky.social @ash.edu.hematology.org @vjhemonc.bsky.social @uthealthsa.bsky.social
Today’s question!
Check out the answer on the next slide along with its explanation.
#JAK2NegativeErythrocytosis #Erythrocytosis #Hematology #MyeloproliferativeDisorders @vjhemonc.bsky.social @ash.hematology.org @ash.edu.hematology.org @bsochaem.bsky.social @isbt.bsky.social
SFX-01 is therapeutic against #MyeloproliferativeDisorders caused by activating mutations in #Shp2
By HJ Cho, J Smith, C Switzer, P. Eaton and colleagues @qmul.bsky.social
🗞️ doi.org/10.1038/s443...
