Decreased M6A Modification Promotes Progression of Gastrointestinal Stromal Tumor and KIT‐Derived Imatinib Resistance Through FTO‐Regulated Axis The study identifies decreased m6A levels, FTO and lncRNA XIST as critical oncogenic molecules in gastrointestinal stromal tumor (GIST) progression and imatinib resistance, both in vitro and in vivo....

#Article in #MedComm_Oncology
Decreased M6A Modification Promotes Progression of Gastrointestinal Stromal Tumor and KIT-Derived #Imatinib Resistance Through FTO-Regulated Axis doi.org/10.1002/mog2...

#GIST #XIST #KIT #DrugResistance #N6_methyladenosine #FTO #lncRNA