NOX4 Suppresses Ferroptosis Through Regulation of the Pentose Phosphate Pathway in Colorectal Cancer

Scientists identify #NOX4 as a key therapeutic target in #ColorectalCancer, showing that its interaction with #G6PD boosts the #PentosePhosphatePathway, enhances #ROS clearance, suppresses #ferroptosis, and promotes #tumor cell survival.
Read: doi.org/10.1007/s115...