HNMT Promotes the Occurrence and Progression of Nasopharyngeal Carcinoma by Inhibiting the IFN/TXNIP/p53 Axis - Current Medical Science Objective Histamine N-methyltransferase (HNMT) is involved primarily in histamine metabolism, but emerging evidence suggests its potential role in cancer progression. This study investigated the role ...

This study uncovers that #Histamine N-methyltransferase drives #nasopharyngeal #carcinoma by blocking Thioredoxin-interacting protein and p53, disrupting #interferons, revealing HNMT–IFN/TXNIP/p53 axis as a potent #therapeutic target. #medsky

Read: link.springer.com/article/10.1...

Age- and disease severity-associated changes in the nasopharyngeal microbiota of COVID-19 patients Health sciences; Virology

#Medsky🧪 #IDsky #immunosky #publichealth Insights into age-associated dynamics within #nasopharyngeal #microbiota during severe #COVID . @cp-iscience.bsky.social

www.cell.com/iscience/ful...