This is the result of a truly multidisciplinary team 🧑‍🤝‍🧑🧑‍🤝‍🧑, led by @gp83.bsky.social , @dalyaf.bsky.social and @martinfranke.bsky.social and joined by @radaiglesiaslab.bsky.social and myself for this new chapter.
#GeneticDiagnostics #NonCodingGenome #RareDisease
3/3

Unveiling the regulatory potential of the non-coding genome: Insights from the Human Genome Project to precision medicine

An overview on the role of the #NonCodingGenome in #GeneRegulation, its implications for understanding the #pathogenesis of complex diseases, and its potential in developing targeted therapeutic interventions. #NextGenSequencing #Genomics #medsky @nihfellowsunited.bsky.social

buff.ly/XMNmXru

DUX4, the rockstar of embryonic genome activation?

ijdb.ehu.eus/article/2302...

by Sonja Nykänen & Sanna Vuoristo

🔑 Double Homeobox 4 (DUX4), embryo development, embryonic genome activation #GenomeActivation, gene regulation #GeneRegulation, non-coding genome #NonCodingGenome

Update of the FANTOM web resource: enhancement for studying noncoding genomes Abstract. The FANTOM web resource (https://fantom.gsc.riken.jp/) has been a unique resource for studying mammalian genomes, which is built on the research

Update of the FANTOM web resource: enhancement for studying noncoding genomes. #Fantom #NoncodingGenome #NAR 🧬
academic.oup.com/nar/advance-...

2025 Decoding Microproteins Across Evolution and Disease Conference GRC The 2025 Gordon Research Conference on Decoding Microproteins Across Evolution and Disease will be held in Castelldefels, Barcelona Spain. Apply today to reserve your spot.

Registration is OPEN for the Gordon Research Conference on #Microproteins! Scholarships are available.

Get involved now while spaces are still available.
You won't want to miss this!

🧪
🧬 💻
🔎 microproteins
#darkgenome
#NoncodingGenome
#Cancer
#Proteomics
#sORFs
#Ribose

www.grc.org/decoding-mic...

Accelerated evolution of CES7, a gene encoding a novel major urinary protein in the cat family - PubMed Cauxin is a novel urinary protein recently identified in the domestic cat that regulates the excretion of felinine, a pheromone precursor involved in sociochemical communication and territorial markin...

Cat-cat interactions are mostly dominated by pheromones and not meows.

This is really fascinating because of the genomics for all #darkgenome, #noncodinggenome, #denovogene folks.

Cats rapidly evolved CES7 as a urinary pheromone for cat-cat communication.

4/

pubmed.ncbi.nlm.nih.gov/20966115/

#DarkGenome #NoncodingGenome fanatics - this one is for you. 👇

🧬 💻
🧪
#genomics
#bioinformatics