Stuart Blacksell

#ResearchHighlight from Stuart Blacksell @moru-mip.bsky.social

Optimization of heat inactivation protocols for #Orientia and #Rickettsia species

Read more 👉 www.ndm.ac/tropmed.res-hi
Full publication 👉 www.nature.com/articles/s41...

#ScrubTyphus #orientia species mostly Asia-Pacific, but emerging evidence of worldwide distribution in tropical/subtropical zone. Leading cause of treatable undifferentiated febrile illness in SE Asia #Orientia #tsutsugamushi obligate intracellular pathogen transmitted by trombiculid mites

#Scrub #typhus vector: mite, organism: #Orientia tsutsugamushi
occurs 7–10d post bite of an infected mite
-pathogenesis increased vascular permeability & perivasculitis of small blood vessels, variable cardiac complications can be caused by damage to cardiac tissue