A nuclear RNA degradation code is recognized by PAXT for eukaryotic transcriptome surveillance Soles et al. demonstrate that the combination of a 5′ splice site and a poly(A) junction constitutes a nuclear RNA degradation code that targets RNAs for degradation by the PAXT adaptor and the RNA ex...

Nice!
A nuclear #RNA #degradation #code is recognized by #PAXT for eukaryotic #transcriptome #surveillance: Molecular Cell www.cell.com/molecular-ce...

RNA 3′end tailing safeguards cells against products of pervasive transcription termination - Nature Communications Pervasive transcription generates numerous unadenylated RNAs, usually degraded by the NEXT/nuclear exosome pathway. Here, the authors show that, upon NEXT inactivation, these RNAs are removed by compe...

Interesting! #RNADecay #NEXT #PAXT #RNAExosome #RNA
www.nature.com/articles/s41...