A phosphodiesterase 4 (PDE4) inhibitor, amlexanox, reduces neuroinflammation and neuronal death after pilocarpine-induced seizure Epilepsy, a complex neurological disorder, is characterized by recurrent seizures caused by aberrant electrical activity in the brain. Central to this study is the role of lysosomal dysfunction in epi...

A phosphodiesterase 4 ( #PDE4) inhibitor, amlexanox, reduces neuroinflammation and neuronal death after pilocarpine-induced seizure

pmc.ncbi.nlm.nih.gov/articles/PMC...

Moracin M derivative targeting PDE4 for the treatment of psoriasis LW, a Moracin M derivative, inhibits Phosphodiesterase-4 (PDE4), reduces inflammation, and improves psoriasis symptoms, showing strong therapeutic potential with fewer side effects.

LW, a #MoracinM derivative, inhibits #PDE4, reduces inflammation, and improves psoriasis symptoms, showing strong therapeutic potential with fewer side effects.

Read More: tinyurl.com/3pvwextj

#PDE4inhibitor #psoriasis #inflammatoryfactor #AMMJournal @scienceopen.bsky.social