Now in Small: pH-dependent remodeling of #LNP membranes.
#Constant-pH MD reveals effect of LNP-lipids on the LNP #pKa.
Video: Membrane remodeling from pH 5 → pH 7
Blue = charged aminolipids | Yellow = neutral | Green = cholesterol
#lipids @fau.de @m-a-r-i-u-s.bsky.social
doi.org/10.1002/smll...
@richardbranson.bsky.social why is your stock so low? Could you market the opposite of the Epstein list? Something that under no circumstance is Trump allowed in on the action. #Epstein-List #safety-in-market #Self-preservation #invest #taco #dump-Trump #PKA #rsk #Woody's-Gamertag
#PKA obok bazy ocenianych kierunków pka.edu.pl/ocena/baza-u... opublikowała osobno wykaz ocen negatywnych pka.edu.pl/wp-content/u... jest też linki do RAD-onu z wykazem uprawnień do prowadzenia studiów
How many runways do you see for Napaskiak airport (USA) ? : The answer is on https://www.bigorre.org/aero/meteo/papk/en #napaskiak #usa #napaskiakairport #papk #pka #airport #aviation #avgeek vl
Salt and sugar are probably too acidic. #pKa
🧬 #PKA has long been considered essential for hippocampus-dependent long-term memory, but deleterious for #WM.
We demonstrate that PKA activation in the striatum is beneficial for working memory capacity. This calls for targeted, region-specific PKA modulators — intelligent PKA agents.
This inverted-U dose-response curve is well-known in the literature — nothing new here.
🔍 So, what’s new?
✔️ Low-dose D1 stimulation expands MC via #PKA activation in the striatum.
We show that striatal PKA activation is both necessary and sufficient to enhance memory capacity.
Low doses? 🎯 Boost memory.
High doses? 🚫 Impair it.
A game-changer for cognitive enhancement strategies in schizophrenia and beyond!
🔗Read the full article here: doi.org/10.1038/s414...
#Neuroscience #Memory #Dopamine #Striatum #PKA #Schizophrenia #SystemsPharmacology
⚙️ Aganitha Igniva™ AI Agents for CMC: Accelerating formulation design & enabling digital twins
✅ Reaction modeling: Yield prediction, catalyst selection
✅ Formulations: #pKa prediction, ASDs stability, #LNP screening, #CSP
✅ Digital twins: Simulating unit operations
#maschinenkrieger
#マシーネンクリーガー
#PKA
#ウェーブ 版お手付き
コクピット周りのパーツ数が日東版の3倍ありますw
ちなみに日東版との比較
見慣れないせいかウェーブがデカくて違和感全開
SAFSに合わせたんでしょうけどSAFSがデカイのよ…
#プラモデル #Pramo
Binding of a Co(III) Metalloporphyrin to Amines in Water: Influence of the pKa and Aromaticity of the Ligand, and pH-Modulated Allosteric Effect | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Tomas and co-workers @InorgChem #cobalt #metalloprophyrin #amines #pKa #aromaticity #pH
Zatrważające jest to, że prowadzenie takiego kierunku studiów obwarowane jest olbrzymią ilością przepisów. I organ nadzorujący na to pozwala - nadal!! #MZ #MNISW #PKA
Jerry Clarke KOs Vernon Mason with spinning back kick
Long pants kickboxing!
#PKA #Kickboxing
🔊 #NowPlaying on #BBC6Music's #LaurenLaverne
PKA:
🎵 Temperature Rising
#PKA
▶️ 🪄 Automagic 🔊 show 📻 playlist on Spotify
▶️ Song on #Bandcamp:
Organic material is more acidic than we realize. #WaterIsntVanilla #pKa #HeavyMetals
